Multiple Clustered Dermatofibromas Following Ustekinumab Treatment for Psoriasis Vulgaris

Ruiz‐Villaverde, Ricardo; Sánchez‐Cano, Daniel

doi:10.18295/squmj.2017.17.03.025

Cited by 5 publications

(4 citation statements)

References 12 publications

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“…Of note, some cases of clustered or plaque-like dermatofibromas appear to be different from the MCDF/PLDF/PLMT group. Most notable among these are four case reports of patients who also had multiple clustered or plaque-like dermatofibromas that, however, differed by their eruptive time course and, in three cases, by coincidence with the administration of immunosuppressive medication [27][28][29][30]. Our patient clearly does not fit into this group because her plaque exhibited very slow growth, and she had taken immunomodulatory medication only in the recent past.…”

Section: Discussionmentioning

confidence: 73%

Plaque-Like Dermatofibroma: Case Report of a Rare Entity

et al. 2021

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Section: Discussionmentioning

confidence: 73%

Plaque-Like Dermatofibroma: Case Report of a Rare Entity

et al. 2021

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“…Full‐texts of 11 articles were not accessible and 30 articles were irrelevant after assessing the full‐text. Eventually, 96 studies fulfilled the eligibility criteria and were included [1–96] (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

Multiple dermatofibromas, associated clinical and histological characteristics: A systematic review

Seifi

Kalantari

Etesami

2022

J Deutsche Derma Gesell

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Summary Multiple dermatofibromas (DFs) are rare benign fibrohistiocytic lesions characterized by asymptomatic hyperpigmented nodules. Several diseases, like systemic lupus erythematosus (SLE) and human immunodeficiency virus (HIV) infection, are found to be associated with multiple DFs. Here, we designed a systematic review by an electronic search of PubMed and Embase databases to select case reports of multiple DFs (29 May 2021). From 2,145 initially found articles, 96 studies (106 cases) were included. We classified multiple DFs (>1 DF lesion) into four subtypes and separately investigated clinical characteristics of each one: multiple eruptive DFs (MEDFs) (n = 45), multiple (n = 41), multiple clustered DFs (MCDFs) (n = 18), and giant combined (n = 2). The patients’ mean age was 38.3 ± 14.7 years. The majority were female (61.3 %). The lesions were commonly on the trunk and extremities (36.8 %). MEDFs (n = 36) had the most rapid disease onset (2.0 ± 6.6 years). Immunosuppression induced by either HIV (10.3 %) and hematologic malignancy (9.4 %) or immunosuppressive drugs (23.4 %) along with SLE (19.8 %) were the most observed associations. However, 66.7 % of the MCDF patients were otherwise healthy individuals. As for disease management, surgery and follow‐up were the preferred options. Most of the cases showed neither resolution nor development of new lesions in follow‐up.

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“…That is because although techniques such as cryotherapy, intra-lesional steroids, surgery and phototherapy have been researched, their success is still variable. In the case of surgery, the lesions end up recurring, so they are only recommended in cases of discomfort and/or aesthetic complaints reported by the patient [5,9,13,14]. In agreement with the patient, we opted for observation and regularly follow-up.…”

Section: Discussionmentioning

confidence: 99%

Multiple Clustered and Focally Atrophic Dermatofibromas: Case Report and Literature Review

Amorim¹,

Itaya²,

Itaya³

et al. 2020

CRDOA

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We present a case of a 50 year-old woman with multiple erythematous and hyperpigmented plaques, with achromic and slightly atrophic centers, restricted to a body segment. Dermoscopy showed a pigmented network surrounding a central scar-like patch. Histopathology, complemented by immunohistochemical profile was compatible with dermatofibromas, arranged in a multiple clustered form. Relevant literature on the topic was reviewed. Meshterms: Factor 13a Positivity; Benign Fibrous Histiocytoma; Multiple clustered dermatofibroma; Segmental Distribution

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Multiple Clustered Dermatofibromas Following Ustekinumab Treatment for Psoriasis Vulgaris

Cited by 5 publications

References 12 publications

Plaque-Like Dermatofibroma: Case Report of a Rare Entity

Plaque-Like Dermatofibroma: Case Report of a Rare Entity

Multiple dermatofibromas, associated clinical and histological characteristics: A systematic review

Multiple Clustered and Focally Atrophic Dermatofibromas: Case Report and Literature Review

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