Multiple Calcified Pulmonary Nodules in an Elderly Man

Panella, Joseph S.

doi:10.1001/jama.1980.03310220057033

Cited by 6 publications

(4 citation statements)

References 2 publications

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“…On X-rays, the lung metastasis usually appears as multiple round or oval-shaped nodules with calcification in some cases. However, X-rays have limitations in detecting smaller lesions and providing detailed information [26,[37][38][39][40][41]. Even though, in some cases, chest X-ray may be part of the initial diagnostic workup or used for monitoring purposes.…”

Section: Imaging Modalitiesmentioning

confidence: 99%

“…Moreover, emerging evidence supports the efficacy of stereotactic ablative radiotherapy (SABR), also known as stereotactic body radiotherapy (SBRT), in delivering high doses of radiation in a limited number of treatment sessions, thereby providing a convenient and effective treatment option for patients [83][84][85]. By delivering focused radiation to metastatic lesions, several studies showed that radiotherapy can induce tumor regression, improve local control, and complete resolution for patients with prostate cancer lung metastasis [12,15,24,29,41,49,73,87].…”

Section: Metastasis-directed Therapies (Mdt)mentioning

confidence: 99%

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Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies

Mahmoud,

Moustafa,

Day

et al. 2024

Preprint

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Prostate cancer lung metastasis represents a clinical conundrum due to their implication of advanced disease progression and the complexities they introduce in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requiring tailored therapeutic strategies to address the unique characteristics of metastatic lesions. This review seeks to synthesize the current state of knowledge surrounding prostate cancer metastasis to the lung, shedding light on the diverse array of clinical presentations encountered, ranging from subtle radiological findings to overt symptomatic manifestations. By examining the diagnostic modalities utilized in identifying this metastasis, including advanced imaging techniques and histopathological analyses, the review aims to provide insights into the diagnostic landscape and the challenges associated with accurately characterizing lung metastatic lesions in prostate cancer patients. Moreover, the review delves into the nuances of therapeutic interventions employed in managing prostate cancer lung metastasis, encompassing systemic treatments such as hormonal therapies and chemotherapy, as well as metastasis-directed therapies including surgery and radiotherapy.

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Section: Imaging Modalitiesmentioning

confidence: 99%

Section: Metastasis-directed Therapies (Mdt)mentioning

confidence: 99%

Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies

Mahmoud,

Moustafa,

Day

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…On X-rays, the lung metastasis usually appears as multiple round or oval-shaped nodules with calcification in some cases. However, X-rays have limitations in detecting smaller lesions and providing detailed information [ 26 , 62 , 63 , 65 , 67 , 70 ]. Even though, in some cases, chest X-ray may be part of the initial diagnostic workup or used for monitoring purposes.…”

Section: Prostate Cancer Lung Metastasis Presentationsmentioning

confidence: 99%

“…Moreover, emerging evidence supports the efficacy of stereotactic ablative radiotherapy (SABR), also known as stereotactic body radiotherapy (SBRT), in delivering high doses of radiation in a limited number of treatment sessions, thereby providing a convenient and effective treatment option for patients [ 52 , 58 , 100 , 101 , 102 , 103 , 104 ]. By delivering focused radiation to metastatic lesions, several studies showed that radiotherapy can induce tumor regression, improve local control, and complete resolution for patients with prostate cancer lung metastasis [ 12 , 15 , 24 , 29 , 38 , 70 , 71 , 102 , 103 , 104 ].…”

Section: Treatment Approachesmentioning

confidence: 99%

Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies

Mahmoud,

Moustafa,

Day

et al. 2024

Cancers

View full text Add to dashboard Cite

Prostate cancer lung metastasis represents a clinical conundrum due to its implications for advanced disease progression and the complexities it introduces in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requiring tailored therapeutic strategies to address the unique characteristics of metastatic lesions. This review seeks to synthesize the current state of knowledge surrounding prostate cancer metastasis to the lung, shedding light on the diverse array of clinical presentations encountered, ranging from subtle radiological findings to overt symptomatic manifestations. By examining the diagnostic modalities utilized in identifying this metastasis, including advanced imaging techniques and histopathological analyses, this review aims to provide insights into the diagnostic landscape and the challenges associated with accurately characterizing lung metastatic lesions in prostate cancer patients. Moreover, this review delves into the nuances of therapeutic interventions employed in managing prostate cancer lung metastasis, encompassing systemic treatments such as hormonal therapies and chemotherapy, as well as metastasis-directed therapies including surgery and radiotherapy.

show abstract