Multiple bronchioloalveolar carcinomas in acromegaly: A potential role of insulin-like growth factor I in carcinogenesis

Motoi, Noriko; Kishi, Kazuma; Fujii, Takeshi; Tsuboi, Eiyasu; Ohashi, Kenichi; Yoshimura, Kazuya

doi:10.1016/j.lungcan.2006.07.011

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…25 Bronchial carcinoids, SCLC, bronchioloalveolar carcinoma, and epidermoid carcinoma are the types of lung cancer associated with acromegaly. [26][27][28] Diagnosis of ectopic acromegaly is by detection of higher plasma levels of GHRH in cases of GHRH releasing tumours; whereas in ectopic GH secretion, evaluation of high GH levels, which are not suppressed by glucose load in presence of low or undetectable GHRH levels. 25 The most effective treatment option is the complete surgical removal of the underlying tumour.…”

Section: Acromegalymentioning

confidence: 99%

The Paraneoplastic syndromes in Lung cancers

Neralla¹

2023

Respiratory Med

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Section: Acromegalymentioning

confidence: 99%

The Paraneoplastic syndromes in Lung cancers

Neralla¹

2023

Respiratory Med

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Paraneoplastic syndromes associated with lung cancer Nobuhiro Kanaji, Naoki Watanabe, Nobuyuki Kita, Shuji Bandoh, Akira Tadokoro, Tomoya Ishii, Hiroaki Dobashi, Takuya Matsunaga

Kanaji¹,

Watanabe²,

Kita³

et al. 2014

WJCO

171

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Paraneoplastic syndromes are signs or symptoms that occur as a result of organ or tissue damage at locations remote from the site of the primary tumor or metastases. Paraneoplastic syndromes associated with lung cancer can impair various organ functions and include neurologic, endocrine, dermatologic, rheumatologic, hematologic, and ophthalmological syndromes, as well as glomerulopathy and coagulopathy (Trousseau's syndrome). The histological type of lung cancer is generally dependent on the associated syndrome, the two most common of which are humoral hypercalcemia of malignancy in squamous cell carcinoma and the syndrome of inappropriate antidiuretic hormone secretion in small cell lung cancer. The symptoms often precede the diagnosis of the associated lung cancer, especially when the symptoms are neurologic or dermatologic. The proposed mechanisms of paraneoplastic processes include the aberrant release of humoral mediators, such as hormones and hormone-like peptides, cytokines, and antibodies. Treating the underlying cancer is generally the most effective therapy for paraneoplastic syndromes, and treatment soon after symptom onset appears to offer the best potential for symptom improvement. In this article, we review the diagnosis, potential mechanisms, and treatments of a wide variety of paraneoplastic syndromes associated with lung cancer.

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Multiple bronchioloalveolar carcinomas in acromegaly: A potential role of insulin-like growth factor I in carcinogenesis

Cited by 2 publications

References 23 publications

The Paraneoplastic syndromes in Lung cancers

The Paraneoplastic syndromes in Lung cancers

Paraneoplastic syndromes associated with lung cancer Nobuhiro Kanaji, Naoki Watanabe, Nobuyuki Kita, Shuji Bandoh, Akira Tadokoro, Tomoya Ishii, Hiroaki Dobashi, Takuya Matsunaga

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