Multiple Bilateral Apocrine Cystadenomas of the Lower Eyelids

Sacks, Evan; Jakobiec, Frederick A.; McMillan, Reagan; Fraunfelder, Frederick “Fritz” T.; Iwamoto, Takeo

doi:10.1016/s0161-6420(87)33501-8

Cited by 33 publications

(10 citation statements)

References 20 publications

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“…In addition, the apocrine hidrocystoma tend to have bluish colour with yellow apical deposits. 12 Our observations indicate that a typical eccrine hidrocystoma of the eyelid manifests in an adult as a solitary clear cystic lesion although cases with simultaneous bilateral involvement have also been reported. 13 The tumour is usually located along the medial or lateral aspect of the eyelid.…”

Section: Discussionmentioning

confidence: 49%

Eccrine hidrocystoma of the eyelid

Singh

McCloskey

Parsons

et al. 2004

Eye

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Aim To report on the clinical features of eccrine hidrocystoma involving the eyelid. Methods Data on a series of consecutive patients with histopathologically confirmed diagnosis were reviewed. Results Among 34 patients, 69 tumours were identified. The mean age at diagnosis was 59 years (range 39-91 years). The majority (71%) of patients had only a single tumour. The tumours appeared as a small (median size ¼ 1 mm) clear cystic lesion with 87% located near the eyelid margin. Conclusions The eccrine hidrocystoma is a benign small cystic tumour that characteristically occurs close to but does not involve the eyelid margin.

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Section: Discussionmentioning

confidence: 49%

Eccrine hidrocystoma of the eyelid

Singh

McCloskey

Parsons

et al. 2004

Eye

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“…Clinical features, progression and diagnosis are in agreement with other cases reported in the literature. 6,8,9 Surgical excision is the treatment of choice in the case of single lesions. 13 To the best of our knowledge, the surgical technique for removal of these lesions has not been described in any reports published in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…6,8,9 The most usual site is on the lower eyelids. 10 The time between the first appearance of the lesion and reaching clinical diagnosis varies from one to five years; however, it should be emphasized that this figure is imprecise since in many cases onset of the lesion's growth was not observed by the physician, given that the lesion is usually asymptomatic.…”

Section: Introductionmentioning

confidence: 99%

Hidrocistoma: conduta cirúrgica na lesão palpebral cística

Júnior¹,

Batista²,

Calafiori³

et al. 2010

An. Bras. Dermatol.

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This report describes the case of a hidrocystoma of the eyelid and the surgical technique used in the therapeutical management of benign cystic lesions of the eyelids. Hidrocystomas are relatively common benign lesions of the eyelids, principally the lower eyelid. They are more common in females over thirty years of age. Diagnosis is clinical and when there is a single lesion, surgery is the treatment of choice. The surgical technique used should be described in greater detail, since it offers good esthetic results and a low risk of recurrence. Keywords: Eyelid neoplasms; Hidrocystoma; Hidrocystoma/diagnostic; Hidrocystoma/etiology; Hidrocystoma/surgery; Sweat glands Resumo: Relato de caso de hidrocistoma palpebral e apresentação de técnica cirúrgica na conduta terapêutica dos tumores císticos benignos da pálpebra. Os hidrocistomas são tumores benignos relativamente frequentes nas pálpebras, principalmente, na pálpebra inferior, com maior prevalência no sexo feminino e a partir da quarta década de vida. O diagnóstico é clínico e, em casos de lesão única, a conduta cirúrgica é o tratamento de escolha. Deve-se descrever melhor a técnica cirúrgica utilizada, pois traz bons resultados estéticos e menor risco de recidiva.

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“…The majority of eyelid hidrocystomas are clear, milky, or show a bluish discoloration because of the Tyndall effect but clear fluid on lancing, 2,9 whereas eyelid hidrocystomas showing a darker clinical appearance contain pigmented (brown) cyst contents. 11,14,15,17,[26][27][28][29][30][31][32][33] Like typical eyelid hidrocystomas, this group of singular cases of pigmented hidrocystomas did not show a sex, site, or side predilection or more frequent occurrence of multiple cysts. However, it is suspected that closer examination and more precise description of apocrine hidrocystomas would result in detection of a greater number and variety of colored cysts.…”

Section: Cells (3 Cases and 3 Controls)mentioning

confidence: 98%

Pigmented Eyelid Cysts Revisited

Al‐Rohil

Meyer

Slodkowska

et al. 2014

The American Journal of Dermatopathology

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A minority of eyelid hidrocystomas are pigmented containing brown-black contents. Chromhidrosis describes the excretion of colored secretions composed of lipofuscin pigments in apocrine gland-rich anatomic locations. The objective of this study is to evaluate the clinicopathologic features of pigmented eyelid cysts. A case-control study was conducted, examining consecutive pigmented and nonpigmented eyelid hidrocystoma excision specimens. Over a 4-year period, 9 pigmented eyelid hidrocystomas were identified, representing 13% (9/70) of all hidrocystoma excisions. Compared to controls (n = 14), no difference existed for age [mean age 59 (44-78 years) vs. 60 (42-82 years)] or size [mean diameter 2.3 (1-4 mm) vs. 2.7 (1-5 mm)] (pigmented vs. nonpigmented, respectively), but a trend for female, left side, and lower lid predominance for pigmented hidrocystomas existed: 8:1 versus 7:7 F:M; 7:2 versus 7:7 left:right; 8:1 versus 9:5 lower:upper eyelid (pigmented vs. nonpigmented, respectively). Clinically, the pigmented cysts' color varied from dark blue, brown, and to black, and on gross examination, they expressed dark brown to black granular liquid contents. Applying histologic criteria of Jakobiec and Zakka, 8 of 9 and 14 of 14 pigmented and nonpigmented hidrocystomas were of apocrine type. Seven of 9 (78%) pigmented cysts and 6 of 14 (43%) nonpigmented hidrocystomas contained granular eosinophilic cyst contents and/or intracellular cytoplasmic granular pigmented deposits by light microscopy. (The pigmented cyst contents did not survive processing in 2 cases.) By histochemistry (periodic acid Schiff with diastase, Sudan Black, and Fite acid-fast positive staining) and ultraviolet fluorescence, these sediments were determined to be lipofuscin pigments. No hidrocystomas had melanin deposits, and one case had hemosiderin deposits in a scarred cyst wall in addition to cyst lipofuscin pigments. In studies of chromhidrosis, both normal and chromhidrotic apocrine glands contain lipofuscin pigments; the sole difference lies in the amount of lipofuscin granules. Similarly, for eyelid apocrine hidrocystomas, lipofuscin pigments exist in both groups. Presumptively, the amount of lipofuscin and degree of its oxidation distinguish pigmented from nonpigmented apocrine hidrocystomas.

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Multiple Bilateral Apocrine Cystadenomas of the Lower Eyelids

Cited by 33 publications

References 20 publications

Eccrine hidrocystoma of the eyelid

Eccrine hidrocystoma of the eyelid

Hidrocistoma: conduta cirúrgica na lesão palpebral cística

Pigmented Eyelid Cysts Revisited

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