OBJECTIVE. The purposeof this investigationwasto determinethe prevalenceof lower esophagealmucosal rings and to correlate the relationship between these mucosal rings and thepresenceandanatomiclevel of symptomsevokedusinga marshmallowbolus. SUBJECTS AND METHODS. Our prospective studyincluded130 patientswho under went bariumexaminationof the esophagus. All patientscompleteda questionnaireregarding the anatomic location of their symptoms of dysphagia. In addition to a multiphasic examina tion of the esophagus, all patients also underwent fluoroscopic observation and videotaping while swallowing a marshmallow bolus; any symptoms that were provoked were recorded.RESULTS. Lower esophageal mucosalringswere shownin 26 (20%) of the 130 patients. The diameterof the ringswas 9â€"12 mm in six patients,13â€"20 mm in 18 patients,and larger than 20 mm in two patients. In 16 (62%) of the 26 patients, a marshmallow bolus became im pacted at the ring; the impaction caused dysphagia in 12 (75%) of the I6 patients. In these 12 patients, dysphagia was referred to the neck in seven,the sternal angle in two, the mid chest in two, and the lower chest in one patient. None of the 12 patients had a pharyngeal or cervical esophageal abnormality that would account for their symptoms.CONCLUSION. Becauseproximal referral of symptomsis common in patientswith loweresophageal mucosalrings,a thoroughradiographicexaminationof theentireesophagus and esophagogastricregion is required regardlessof the level of their swallowing complaints.