Multiparametric-MRI as a comprehensive study in evaluation, characterization &amp; local staging of urinary bladder carcinomas

Afifi, A. M.; Maksoud, Tarek Abdel Samie Abdel; El-Noueam, Khaled I.; Ataa, Mohamed A.; Abdallah, Dina

doi:10.1016/j.ejrnm.2017.01.011

Cited by 10 publications

(17 citation statements)

References 30 publications

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“…In the study conducted by Takeuchi et al [14] on 52 patients with bladder tumor using 1.5-T MRI, they found that the overall diagnostic accuracy of T2WI in local T staging of bladder tumor was 67%. A study by Afifi et al [15] using 1.5-T magnet, conducted on 50 patients with bladder cancer, showed T2 staging diagnostic accuracy of 52%. Another interesting study by Abou-El-Ghar et al [16] using 1.5-T MRI conducted on larger number of patients (130 patients) showed T2 staging diagnostic accuracy of 39.6%.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic performance of 3-tesla multiparametric MRI for assessment of the bladder cancer T stage and histologic grade

Badawy

Farg

Gadelhak

et al. 2020

Egypt J Radiol Nucl Med

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Background Preoperative staging of urinary bladder carcinomas using TNM system is crucial in the management of bladder cancer which is determined mainly by stage and grade of tumor at diagnosis. We aim to evaluate the diagnostic accuracy of multiparametric MRI (mp-MRI) for assessment of the bladder cancer T stage and histologic grade. Results The overall T2-WI diagnostic accuracy for the T stage was 72.3%, increased to be 87.1% for contrast-enhanced images, and 92.6% for DWI, reaching the maximum accuracy 94.5% using the combined multi-parametric MRI technique. Diagnostic accuracies of mp-MRI in differentiating superficial from muscle-invasive (91%) and organ-confined from non-organ confined tumors (92%) were superior to DW-MRI (89% and 87%), DCE-MRI (84% and 83%), and T2W-MRI (74% and 71%), respectively. The agreement between MRI findings and histopathological staging was greater in mp-MRI (k = 0.91; excellent agreement) than in DW-MRI (k = 0.77; moderate agreement), DCE-MRI (k = 0.76; substantial agreement), and T2W-MRI (k = 0.53; fair agreement). Conclusion Mp-MRI provides useful information for evaluating the local T stages of bladder cancer and can predict the histological grades of urinary bladder cancers with high diagnostic accuracy.

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Section: Discussionmentioning

confidence: 99%

Diagnostic performance of 3-tesla multiparametric MRI for assessment of the bladder cancer T stage and histologic grade

Badawy

Farg

Gadelhak

et al. 2020

Egypt J Radiol Nucl Med

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“…For high-grade non-muscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC), MRI may detect and stage tumors with high sensitivity and specificity (7). mpMRI has demonstrated high diagnostic accuracy in differentiating NMIBC from MIBC and organ-confined disease from non-organ confined disease (8); exceeding that of T2 weighted imaging (T2W) or diffusion weighted imaging (DWI)-MRI used alone (8). Compared with CT, MRI offers improved soft-tissue resolution, making it easy to distinguish between NMIBC and MIBC.…”

Section: Discussionmentioning

confidence: 99%

“…There are a number of reports on the usefulness of mpMRI for the detection of tumor recurrence (9) and differentiation of non-muscle invasive UC from muscle-invasive UC (10,11). Afifi et al (8) reported on the usefulness of mpMRI in detecting metastatic lymph nodes. The largest size of the metastatic lymph nodes detected was 42 mm, and lymph nodes with low apparent diffusion coefficient values were considered positive (8).…”

Section: Discussionmentioning

confidence: 99%

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Usefulness of multi‑parametric MRI for diagnosis of invasive urothelial cancer: Case reports of bladder and ureteral cancer

Hoshi¹,

Horio²,

Numahata

et al. 2018

mol clin onc

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The presence or absence of metastasis has critical implications for therapeutic decision-making in urothelial cancer (UC). Conventional magnetic resonance imaging (MRI) utilizing anatomic T1-and T2-weighted images has modest efficacy in detecting lymph node and distant metastases in UC. However, incorporation of functional techniques including diffusion weighted imaging and dynamic contrast-enhanced imaging, may improve the accuracy of lesion detection and staging. Multiparametric (mp)MRI is widely used in the imaging of prostate and breast cancers, though its usefulness in UC has yet to be fully elucidated. The present study reports on mpMRI in the context of two cases of bladder and ureteral cancer, and imaging results with pathological diagnosis.

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“…таблицу), сообщив, что чувствительность, специфичность и точность метода в диагностике РМП составили 90-98, 92-93 и 91-97% соответственно [21][22][23]. По данным A.H. Afifi et al, значение ИКД было значительно ниже у high-grade опухолей (0,73 ×10 -3 мм 2 /с), чем у low-grade карцином (1,24 ×10 -3 мм 2 /с), и при этом отличалось от такового у нормальной стенки (1,54 ×10 -3 мм 2 /с) и мочи (2,98 ×10 -3 мм 2 /с) [24]. На диффузионно-взвешенных изображениях с высоким b-фактором МР-сигнал фоновых тканей в большей степени подавляется, а уротелиальная опухоль демонстрирует очень высокий уровень сигнала, при этом область, имеющая высокий МРсигнал, коррелирует с объемом опухоли.…”

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Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Staging of Bladder Cancer

Фролова

Григорьев

Величко

et al. 2020

Vestn. rentgenol. radiol.

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This scientific review assesses the current diagnostic capabilities of diffusion-weighted images used in the magnetic resonance imaging protocol for bladder cancer. It actualizes this impulse sequence employed within the framework of a multiparametric MRI study as one of the functional techniques. The review deals with the possibilities of diffusion-weighted images used in an independent version and in combination with T2-weighted images to visualize a tumor, postoperative changes, and associated pathology. It gives differential diagnostic criteria in identifying the extent of tumor invasion, including that with accuracy assessment according to the measured diffusion coefficient.The sources of the review are publications included in the peer-reviewed databases PubMed, Scopus, eLIBRARY and the open sources Google Scholar, Researchgate.

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Multiparametric-MRI as a comprehensive study in evaluation, characterization & local staging of urinary bladder carcinomas

Cited by 10 publications

References 30 publications

Diagnostic performance of 3-tesla multiparametric MRI for assessment of the bladder cancer T stage and histologic grade

Diagnostic performance of 3-tesla multiparametric MRI for assessment of the bladder cancer T stage and histologic grade

Usefulness of multi‑parametric MRI for diagnosis of invasive urothelial cancer: Case reports of bladder and ureteral cancer

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis and Staging of Bladder Cancer

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