Multiorgan embolisation of a left ventricular thrombus

Extensive Left Ventricular Thrombosis with Concomitant Pulmonary Embolism

“…Intracardiac thrombus formation is a potentially severe complication related to cardiac conditions such as ischemic and non-ischemic cardiomyopathies (with or without manifest heart failure), valvular diseases and atrial fibrillation [3,4]. In the pathophysiology of LVT development the elements of Virchow's triad play the main role: (1) wall motion abnormalities causing slow flow conditions and blood stasis, (2) the presence of local and systemic proinflammatory factors provoking endocardial lesions and (3) hypercoagulability [5,6].…”

“…Cerebral infarction, pulmonary embolism and multi-organ (systemic) embolization were reported as possible complications of LVT [10]. In untreated LVT the risk of embolization is estimated to be around 10-15% in the first three months, while in the case of protrusive, mobile thrombi this percentage can rise up to around 60% [4,11]. Although,…”

“…Cerebral infarction, pulmonary embolism and multi-organ (systemic) embolization were reported as possible complications of LVT [10]. In untreated LVT the risk of embolization is estimated to be around 10-15% in the first three months, while in the case of protrusive, mobile thrombi this percentage can rise up to around 60% [4,11]. Although, under efficient anticoagulation therapy, resolution of thrombi is achieved in a median period of 63 days, it has been shown that late resolution-longer than 1 month-of an apical thrombus is associated with poor long-term survival [12].…”