Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis
Miaomiao Zhang,
Jinghao Zhang,
Haisheng Hu
et al.
Abstract:Background
Monocyte-derived alveolar macrophages (Mo_AMs) are increasingly recognised as potential pathogenic factors for idiopathic pulmonary fibrosis (IPF). While scRNAseq analysis has proven valuable in the transcriptome profiling of Mo_AMs, the integration analysis of multi-omics may provide additional dimensions of understanding of these cellular populations.
Methods
We performed multi-omics analysis on 116 scRNAseq, 119 bulkseq and five scATA… Show more
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