2022
DOI: 10.1371/journal.pone.0276279
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Multimorbidity and depressive symptoms in older adults and the role of social support: Evidence using Canadian Longitudinal Study on Aging (CLSA) data

Abstract: Background The rising prevalence of multimorbidity poses challenges to health systems globally. The objectives of this study were to investigate: 1) the association between multimorbidity and depressive symptoms; and 2) whether social support plays a protective role in this association. Methods A prospective population-based cohort study was conducted to analyze baseline and 3-year follow-up data of 16,729 community dwelling participants aged 65 and above in the Canadian Longitudinal Study of Aging (CLSA). M… Show more

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Cited by 8 publications
(5 citation statements)
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References 83 publications
(128 reference statements)
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“…The co-occurrence of depression and multimorbidity has been described by numerous previous studies 18,28 . Zhang et al (2022) found that multimorbidity was associated with increased odds of having depressive symptoms (adjusted odds ratio of 1.51), and developing depressive symptoms (adjusted odds ratio of 1.65).…”
Section: Discussionmentioning
confidence: 83%
“…The co-occurrence of depression and multimorbidity has been described by numerous previous studies 18,28 . Zhang et al (2022) found that multimorbidity was associated with increased odds of having depressive symptoms (adjusted odds ratio of 1.51), and developing depressive symptoms (adjusted odds ratio of 1.65).…”
Section: Discussionmentioning
confidence: 83%
“…Most current disease management guidelines are designed to address individual health conditions, so several co-morbidities pose challenges for physicians when deciding the patient’s management plan and the choice of antidiabetic drugs while balancing the risks and benefits of polypharmacy [ 12 ]. For patients, a diagnosis of several co-morbidities results in increased medication use, billing burden, costs, and the risk of depression alongside a decline in treatment adherence and quality of life [ 4 , 13 , 14 ].…”
Section: Discussionmentioning
confidence: 99%
“…Response options included “required no help”, “some help”, or are “unable to perform” without assistance 20 . Because few CLSA participants reported any functional impairment, the total OARS score was then used to categorize the respondents’ overall functional capacity as dichotomous (no help required for any activity, as a referent, versus some help or unable to perform at least one activity without assistance), similarly to a previous study using these data 33 . To isolate its effect as both an independent predictor and a covariate of interest, meal preparation impairment was considered separately from other ADLs and IADLs in the OARS scale.…”
Section: Methodsmentioning
confidence: 99%