Multimodality imaging of intermediate lesions: Data from FFR, OCT, NIRS-IVUS

Biały, Dariusz; Wawrzyńska, Magdalena; Arkowski, Jacek; Rogala, Marcin; Proniewska, Klaudia; Wańha, Wojciech; Wojakowski, Wojciech; Roleder, Tomasz

doi:10.5603/cj.a2017.0082

Cited by 2 publications

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“…Thus it may affect final stent expansion and prone redistribution of LLB plaques to the edges of implanted stent edges to make space for the stent. Moreover, as it was shown a correlation between HLB lesions and thin fibrous cap atheroma (TFCA) [12,15], it is also possible that LLB lesions are less prone to embolization into the microcirculation from a thick cap. Indeed, OCT studies have shown that TFCA correlates with type IVa myocardial infarction after PCI [14], and OCT defined TFCA is a strong predictor of periprocedural infarction [10].…”

Section: Discussionmentioning

confidence: 99%

Coronary plaque redistribution after stent implantation is determined by lipid composition: A NIRS-IVUS analysis

et al. 2020

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Background: The composition of plaque impacts the results of stenting. The following study evaluated plaque redistribution related to stent implantation using combined near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) imaging. Methods: The present study included 49 patients (mean age 66 ± 11 years, 75% males) presenting with non-ST elevation myocardial infarction (8%), unstable angina (49%) and stable coronary artery disease (43%). The following parameters were analyzed: mean plaque volume (MPV, mm 3 ), plaque burden (PB, %), remodeling index (RI), and maximal lipid core burden index in a 4 mm segment (maxLCBI 4mm ). High-lipid burden lesions (HLB) were defined as by maxLCBI 4mm > 265 with positive RI. Otherwise plaques were defined as low-lipid burden lesions (LLB). Measurements were done in the target lesion and in 4 mm edges of the stent before and after stent implantation.

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Section: Discussionmentioning

confidence: 99%

Coronary plaque redistribution after stent implantation is determined by lipid composition: A NIRS-IVUS analysis

et al. 2020

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“…Coronary angiography remains the gold standard for the diagnosis of CAD, however, its ability to differentiate ischemic from non-ischemic lesions is limited. In this respect, fractional flow reserve (FFR), which takes into consideration the functional severity of coronary stenosis, outperforms the traditional diagnostic approach, based solely on morphometric assessment [3,4]. Unfortunately, the adoption of FFR in everyday clinical practice is slow and is utilized in only a minority of centers [5,6].…”

Section: Introductionmentioning

confidence: 99%

Alternative methods for functional assessment of intermediate coronary lesions

Zaleska¹,

Kołtowski²,

Maksym³

et al. 2020

Cardiol J.

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Wire-based fractional flow reserve (FFR) is a diagnostic tool used to evaluate the ischemic burden of coronary lesions. Large-scale studies have shown that FFR-guided revascularization is associated with better clinical outcomes. However, wide adoption of this technology is limited due to the considerable cost, additional time needed for setup and performance of the measurement as well as the invasiveness of the procedure which requires pressure wire placement across the lesion into the distal segment of the coronary artery. To overcome these limitations new, promising, and less-/non-invasive methods were developed. These methods are based on computational fluid dynamics analysis and three-dimensional lumen reconstruction. The aim of this paper is to review scientific evidence supporting the clinical safety and efficacy of these techniques, such as instantaneous wave-free ratio, quantitative flow ratio and FFR calculated from computed tomographic angiography.

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Multimodality imaging of intermediate lesions: Data from FFR, OCT, NIRS-IVUS

Abstract: The FFR-negative lesions pose traits of vulnerability as assessed simultaneously by IVUS, OCT and NIRS imaging.

Cited by 2 publications

References 22 publications

Coronary plaque redistribution after stent implantation is determined by lipid composition: A NIRS-IVUS analysis

Coronary plaque redistribution after stent implantation is determined by lipid composition: A NIRS-IVUS analysis

Alternative methods for functional assessment of intermediate coronary lesions

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