“…3 a) shows vertebral ossification center is better than the steady state free precession sequence, especially MIP images can be performed to display ossification centers of the spine and thorax, but the soft tissue and spinal cord cannot be displayed [ 4 ]. Since the SWI images are often blurry because of fetal movement and maternal respiration, they are only used as a secondary means in our hospital [ 4 ]. Fig.…”
Section: Discussionmentioning
confidence: 99%
“…Each centrum is fused by the inferior half and the superior half of the sclerotomes, so the intersegmental vessels are located in the center of the vertebral bodies [ 4 ]. On fetal MR T2WI, the vertebral ossification center is usually shown as a hypointensity in the spinal vertebral region [ 24 ].…”
Section: Discussionmentioning
confidence: 99%
“…Because of more detailed information obtained by the MR, fetal MR could be very useful for the diagnosis and treatment of fetal disease [ 1 – 5 ]. Before evaluating the fetal spine, it is important to understand the development of fetal spine at different GAs [ 4 , 6 ]. We find few of published dates on the appearances of vertebrae and intervertebral space, and most of them were postmortem [ 7 – 13 ].…”
Objective
The aim of this study is to describe MR imaging appearances of the fetal lumbar spine in vivo at different gestational ages (GAs).
Methods
This retrospective study was approved by the Third Affiliated Hospital of Zhengzhou University. We collected MR images and clinical data of 93 fetuses in our hospital. All the MR images were obtained by 3-T MR. All had the mid-sagittal plane of steady state free precession sequence (Trufi) of the lumbar spine, which could show the lumbar vertebra and conus medullaris (CM). Regression analysis was made between GA and heights of lumbar vertebral body ossification center (LVBOC), lengths of LVBOC, and heights of intervertebral gap (IVG).
Results
There were good linear correlations between the heights of LVBOC and GA (P < 0.001), lengths of LVBOC and GA (P < 0.001), and heights of IVG and GA (P < 0.001).
Conclusion
We showed the different development of each LVBOC and IVG which caused the difference of the shape of LVBOC and IVG.
“…3 a) shows vertebral ossification center is better than the steady state free precession sequence, especially MIP images can be performed to display ossification centers of the spine and thorax, but the soft tissue and spinal cord cannot be displayed [ 4 ]. Since the SWI images are often blurry because of fetal movement and maternal respiration, they are only used as a secondary means in our hospital [ 4 ]. Fig.…”
Section: Discussionmentioning
confidence: 99%
“…Each centrum is fused by the inferior half and the superior half of the sclerotomes, so the intersegmental vessels are located in the center of the vertebral bodies [ 4 ]. On fetal MR T2WI, the vertebral ossification center is usually shown as a hypointensity in the spinal vertebral region [ 24 ].…”
Section: Discussionmentioning
confidence: 99%
“…Because of more detailed information obtained by the MR, fetal MR could be very useful for the diagnosis and treatment of fetal disease [ 1 – 5 ]. Before evaluating the fetal spine, it is important to understand the development of fetal spine at different GAs [ 4 , 6 ]. We find few of published dates on the appearances of vertebrae and intervertebral space, and most of them were postmortem [ 7 – 13 ].…”
Objective
The aim of this study is to describe MR imaging appearances of the fetal lumbar spine in vivo at different gestational ages (GAs).
Methods
This retrospective study was approved by the Third Affiliated Hospital of Zhengzhou University. We collected MR images and clinical data of 93 fetuses in our hospital. All the MR images were obtained by 3-T MR. All had the mid-sagittal plane of steady state free precession sequence (Trufi) of the lumbar spine, which could show the lumbar vertebra and conus medullaris (CM). Regression analysis was made between GA and heights of lumbar vertebral body ossification center (LVBOC), lengths of LVBOC, and heights of intervertebral gap (IVG).
Results
There were good linear correlations between the heights of LVBOC and GA (P < 0.001), lengths of LVBOC and GA (P < 0.001), and heights of IVG and GA (P < 0.001).
Conclusion
We showed the different development of each LVBOC and IVG which caused the difference of the shape of LVBOC and IVG.
“…Although some anomalies, such as isolated hemivertebrae, may not be associated with severe symptoms, 3 others may be associated with poor prognosis 4 . Newborns with congenital malformations of the spine and spinal cord are usually treated after birth, and the treatment typically depends on the severity of the deformity and the presence of other related anomalies 5 . Therefore, early accurate diagnosis of congenital fetal abnormalities of the spine and spinal cord allows clinicians to formulate appropriate prenatal and postnatal treatment plans, which are of paramount importance to the functional outcome of the patient 6 …”
Section: Introductionmentioning
confidence: 99%
“…4 Newborns with congenital malformations of the spine and spinal cord are usually treated after birth, and the treatment typically depends on the severity of the deformity and the presence of other related anomalies. 5 Therefore, early accurate diagnosis of congenital fetal abnormalities of the spine and spinal cord allows clinicians to formulate appropriate prenatal and postnatal treatment plans, which are of paramount importance to the functional outcome of the patient. 6 Currently, fetal ultrasonography (US) is used to detect irregular arrangement of the spine, local enlargement of the spinal canal, and abnormal curvature of the spine.…”
Purpose
To determine the diagnostic value of fetal magnetic resonance imaging (MRI) for congenital spine/spinal cord malformations.
Methods
This single‐center retrospective study included 120 cases of fetal spine/spinal cord abnormalities detected using fetal ultrasonography (US) and further examined by fetal MRI between 2016 and 2020. Cases were divided into three groups (congenital spine, spinal cord, and spine + spinal cord malformations) based on US assessment. We analyzed the accuracy of fetal US and MRI relative to postnatal imaging.
Results
The diagnostic accuracy of fetal MRI for fetal spinal cord, spine, and spine + spinal cord malformations was 86.2% (25/29), 89.4% (42/47), and 86.3% (38/44), respectively, and the corresponding rates for fetal US were 51.7% (15/29), 87.2% (41/47), and 68.2% (30/44). The diagnostic accuracy did not differ between fetal MRI and US for congenital spine malformations (p > 0.05); for congenital spinal cord malformations and congenital spine + spinal cord malformations, the diagnostic accuracy was significantly higher for fetal MRI than for fetal US (p < 0.05).
Conclusions
Fetal MRI is effective in the assessment of congenital spine/spinal cord malformations. It can yield information that supplements US findings, especially for congenital spinal cord malformations, and can improve the accuracy of fetal diagnosis.
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