Multimodality Cardiac Imaging Enhances Diagnosis and Management of Recurrent Atrial Myxomas in Carney Complex

Patibandla, Saikrishna; Brito, Daniel; Sloyer, Daniel; Cook, Chris C.; Badhwar, Vinay

doi:10.1016/j.case.2021.03.003

Cited by 1 publication

(2 citation statements)

References 13 publications

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“…Biatrial involvement may occur if the myxoma grows across the patent foramen ovale. Multifocal myxomas in atypical sites have been reported in patients with Carney's complex [26,35]. Metastatic malignant tumors are 22 to 132 times more common than primary cardiac masses and should be considered in every patient with disseminated malignancy [18].…”

Section: Differential Diagnosismentioning

confidence: 99%

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Multimodality Imaging of Cardiac Myxomas

Hrabak-Paar,

Muršić,

Balaško-Josipović

et al. 2024

Rev. Cardiovasc. Med.

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Cardiac myxomas are the most common benign cardiac neoplasms. Echocardiography is the first-line imaging modality used to analyze cardiac masses, allowing the detection of tumor location, size, and mobility. However, additional imaging techniques are required to confirm the diagnosis, evaluate tissue characteristics of the mass, and assess potential invasion of surrounding structures. Secondline imaging includes cardiac magnetic resonance imaging (MRI) and/or computed tomography (CT) depending on availability and the patient's characteristics and preferences. The advantages of CT include its wide availability and fast scanning, which allows good image quality even in patients who have difficulty cooperating. MRI has excellent soft-tissue resolution and is the gold standard technique for noninvasive tissue characterization. In some cases, evaluation of the tumor metabolism using 18F-fluorodeoxyglucose positron emission tomography with CT may be useful, mainly if the differential diagnosis includes primary or metastatic cardiac malignancies. A cardiac myxoma can be identified by its characteristic location within the atria, typically in the left atrium attached to the interatrial septum. The main differential diagnoses include physiological structures in the atria like crista terminalis in the right atrium and the coumadin ridge in the left atrium, intracardiac thrombi, as well as other benign and malignant cardiac tumors. In this review paper, we describe the characteristics of cardiac myxomas identified using multimodality imaging and provide tips on how to differentiate myxomas from other cardiac masses.

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Section: Differential Diagnosismentioning

confidence: 99%

“…Biatrial involvement may occur if the myxoma grows across the patent foramen ovale. Multifocal myxomas in atypical sites have been reported in patients with Carney’s complex [ 26 , 35 ].…”

Section: Differential Diagnosismentioning

confidence: 99%