Multimodal Magnetic-Plasmonic Nanoparticles for Biomedical Applications

Abstract

Magnetic plasmonic nanomaterials are of great interest in the field of biomedicine due to their vast number of potential applications, for example, in molecular imaging, photothermal therapy, magnetic hyperthermia and as drug delivery vehicles. The multimodal nature of these nanoparticles means that they are potentially ideal theranostic agents-i.e., they can be used both as therapeutic and diagnostic tools. This review details progress in the field of magnetic-plasmonic nanomaterials over the past ten years, focusing on significant developments that have been made and outlining the future work that still needs to be done in this fast emerging area. The review describes the main synthetic approaches to each type of magnetic plasmonic nanomaterial and the potential biomedical applications of these hybrid nanomaterials.

Step‐by‐step monitoring of a magnetic and SERS‐active immunosensor assembly for purification and detection of tau protein

“…Over the last 15 years, nanoparticles (NPs) have found numerous applications in biotechnology and medicine . For example, the plasmonic properties of noble metal NPs are used for imaging applications such as Raman spectroscopy to investigate molecules, pathogens, and tissues .…”

Formation of Bimetallic Fe/Au Submicron Particles with Ultrasonic Spray Pyrolysis

“…Several research works have been done for bimetallic Fe/Au nanostructures [1,2], with a strong interest in biomedical applications [3,4], and also with an additional intermediate layer between the magnetic Fe core and the plasmonic Au layer [5,6]. The goal is to enhance or develop a functional material for targeted applications joining two elements in some type of construction, such as core-shell, alloy or otherwise [7,8].…”

“…The goal is to enhance or develop a functional material for targeted applications joining two elements in some type of construction, such as core-shell, alloy or otherwise [7,8]. Joining the properties of these elements produces different effects, such as enhanced catalysis or tunable plasmonic properties, making the hybrid structures useful for a number of applications (catalysis [7], sensors [7], magnetic resonance imaging [3,4,9], photothermal treatment of cancer [3][4][5] and drug delivery systems [3,4,9]). Our previous research studied the production of gold nanoparticles (AuNPs) with Ultrasonic Spray Pyrolysis (USP) extensively [10].…”

“…Adding a ferromagnetic property to the plasmonic nanoparticles has interesting potential uses in various applications, from catalysis to energy conversion [6]. However, the main focus of research for this type of materials is on a wide range of biomedical applications, such as imaging, tissue engineering, cellular sorting, therapy and targeted drug delivery [2][3][4][5][6]16].…”

Computational Study of Sensitivity Enhancement in Surface Plasmon Resonance (SPR) Biosensors by Using the Inclusion of the Core-Shell for Biomaterial Sample Detection

“…Currently, there is increasing interest in the development of magnetic and plasmonic nanoparticles as active materials for biomolecule detection [ 1 ]. A new nanoparticle that combines multiple functions or properties has attracted considerable attention because of its revolutionary technology which enables the sensitivity enhancement of surface plasmon resonance (SPR)-based biosensors.…”