Multimodal imaging of hypertensive chorioretinopathy by swept-source optical coherence tomography and optical coherence tomography angiography

Rotsos, Tryfon; Andreanos, Konstantinos; Blounas, Stelios; Brοuzas, Dimitrios; Ladas, Dimitrios S; Ladas, Ioannis

doi:10.1097/md.0000000000008110

Cited by 20 publications

(23 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Numerous studies on diabetes mellitus, glaucoma, retinal venous obstruction, and other diseases with vascular involvement using OCTA have been published. 10,11 Recently, two groups have studied the role of OCTA in assessing organ damage that may have been caused by AHT. 12,13 The objective of this study was to evaluate differences in papillary and macular anatomy, nerve fiber layer thickness, ganglion cell complex (GCC), and perfusion density (PD) in healthy patients, low-risk hypertensive patients, and very high risk hypertensive patients using the OCTA technique.…”

Section: Introductionmentioning

confidence: 99%

Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

Pascual-Prieto

Burgos-Blasco

Sánchez-Torija

et al. 2019

European Journal of Ophthalmology

View full text Add to dashboard Cite

Objective: To evaluate the potential utility of perfusion density measurements to discriminate patients with arterial hypertension by cardiovascular risk category. Methods: In this cross-sectional study, one eye per subject was evaluated (N = 73). The study cohort was divided into three groups according to the clinical criteria established by the European Guidelines for Arterial Hypertension: 26 controls, 24 patients with low cardiovascular risk, and 23 patients with very high cardiovascular risk. All patients were examined using RS-3000 Advance optical coherence tomography angiography to analyze macular and peripapillary perfusion density. Results: There were no differences among the three risk groups by sex or age. Decreased macular perfusion density was found at the level of the superficial and deep plexuses (p ⩽ 0.047). No differences were observed in peripapillary perfusion density (p = 0.18). Conclusion: Optical coherence tomography angiography can detect changes in macular perfusion density in patients with hypertension and high cardiovascular risk and might represent a supportive imaging method in the evaluation of the cardiovascular risk in hypertensive patients.

show abstract

Section: Introductionmentioning

confidence: 99%

Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

Pascual-Prieto

Burgos-Blasco

Sánchez-Torija

et al. 2019

European Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

“…Rotsos et al assessed choroidal blood flow at Elschnig points with OCTA and reported the results at 1 month (8) . Similarly, Saito et al compared focal choroidal ischemic areas and reperfusion in hypertensive choroidopathy following treatment with en face OCTA images (9) .…”

Section: Discussionmentioning

confidence: 99%

Optical coherence tomography angiography findings in malignant hypertensive retinopathy

Doğan¹,

Akıdan²,

Erol³

et al. 2019

Arquivos Brasileiros De Oftalmologia

View full text Add to dashboard Cite

A 33-year-old male presented to our clinic with low vision in both eyes that started during the previous week. Visual acuity was 20/63 in the right eye and 20/50 in the left eye. Fundus examination revealed signs of hypertensive retinopathy; thus, a multidisciplinary approach was adopted for the diagnosis and treatment of this patient. We consulted the nephrology and cardiology departments on this case. Upon diagnosing malignant hypertension and renal failure, the patient was put on hemodialysis. His visual acuity was 20/20 at 6 months, whereas foveal assessment on optical coherence tomography angiography revealed neither marked superficial and deep capillary density loss and foveal avascular zone enlargement nor a decrease in disc flow and radial peripapillary capillary density. Early diagnosis and treatment of malignant hypertension are critical in preventing progression of end-organ damage including the eyes. Optical coherence tomography angiography may be useful in cases when fundus fluorescein angiography is relatively contraindicated (e.g., renal failure).

show abstract

“…Гипертоническая хориоретинопатия является хорошо известным проявлением злокачественной гипертензии. Известными проявлениями этого состояния являются пламеобразные кровоизлияния, ватные пятна, наличие интраретинальной жидкости, отслойка пигментного эпителия, пятна Elschnig и отек диска зрительного нерва [23]. Ранее у пациентов с гипертонической хориопатией, вызванной эклампсией, на ОКТ на поверхности пигментного эпителия сетчатки обнаруживались твердые гиперрефлективные структуры [23].…”

Section: гипертоническая ретинопатия при злокачественной артериальнойunclassified

“…Известными проявлениями этого состояния являются пламеобразные кровоизлияния, ватные пятна, наличие интраретинальной жидкости, отслойка пигментного эпителия, пятна Elschnig и отек диска зрительного нерва [23]. Ранее у пациентов с гипертонической хориопатией, вызванной эклампсией, на ОКТ на поверхности пигментного эпителия сетчатки обнаруживались твердые гиперрефлективные структуры [23]. При электронной микроскопии были обнаружены фибринозные отложения на мембране Бруха у экспериментальных обезьян с гипертонической хориопатией во время острой ишемической фазы.…”

Section: гипертоническая ретинопатия при злокачественной артериальнойunclassified

“…Согласно полученным данным, в конце первого месяца лечения почти все начальные очаги уменьшались, кроме пятен Elschnig. Отек диска зрительного нерва уменьшался [26], твердые экссудаты были увеличены в размерах [23].…”

Section: гипертоническая ретинопатия при злокачественной артериальнойunclassified

See 1 more Smart Citation

Modern Aspects of Hypertensive Angioretinopathy

Lk¹,

Воробьева²,

Dgebuadze³

2019

Oftalʹmologiâ

View full text Add to dashboard Cite

This literature review is devoted to modern problems of hypertensive retinopathy with arterial hypertension, as well as hypertensive retinopathy in combination diseases. The latest world studies were analyzed. Particular attention is paid to the clinical disease characteristics at the present stage with the analysis of the arterio-venous ratio, optic nerve edema (with high blood pressure figures) using an automated system, vector analysis, suggesting a new arteriovenous classification, called Web Integration (Wivern). The modern pathogenesis of hypertensive retinopathy, namely the ratio of proangiogenic and anti-angiogenic factors, the role of inflammation (C-reactive protein), the role of endothelin-1, endostatin, interleukin-8 (IL-8), and the main fibroblast growth factor (bFGF ), angiogenin and uric acid. The special importance of fundus registration is reflected with the help of the newest equipment at high figures of arterial pressure in patients with hypertensive retinopathy. It is known that according to the World Health Organization (WHO), mortality rate from cardiovascular diseases is 31 %. Hypertension is the main risk factor for coronary heart disease, myocardial infarction, heart failure, stroke, kidney disease and early death. Questions of eye blood flow in hypertensive angioretinopathy in patients with arterial hypertension (AH) are covered. Hypertensive retinopathy (HR) is a retinal disease that is caused by a prolonged increase blood pressure (BP) and leads to a decrease in vision. The data of pathophysiology are analyzed (arterial hypertension (AH) leads to thickening of the vessels of the inner membrane (intima), to thickening of the medial membrane (media) — hyperplasia of the muscular tissue followed by hyaline degeneration with the development of sclerotic changes). The questions of modern diagnostics with retinal morphological status evaluation (OCT), detection of eye fundus condition with newest fundus camers, pathogenetic aspects are discussed. This review will help to prevent the development of more severe forms of hypertensive retinopathy. This information will allow us to identify the most significant indicators in the early diagnosis of hypertension angioretinopathy.

show abstract

Multimodal imaging of hypertensive chorioretinopathy by swept-source optical coherence tomography and optical coherence tomography angiography

Cited by 20 publications

References 20 publications

Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

Optical coherence tomography angiography findings in malignant hypertensive retinopathy

Modern Aspects of Hypertensive Angioretinopathy

Contact Info

Product

Resources

About