Multimodal imaging of foveal neovascularisation in diabetic retinopathy

Bansal, Aditya; Shankar, Mrinal; Multani, Priyansha; Luthra, Saurabh

doi:10.1111/cxo.12857

Cited by 1 publication

(1 citation statement)

References 6 publications

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“…A study by Schocket et al showed the choroidal volume and choroidal flow were significantly reduced in patients with PDR 7 Hence, foveal NV in PDR is possible and there are a few case reports published in literature. [8][9][10][11][12][13][14][15][16][17][18] Previous case reports depicting foveal NV in PDR have shown involvement of both unilateral and bilateral cases in both type 1 and type 2 diabetics. 10,13 One of the important indications for treating PDR with anti-VEGF therapy according to the Protocol S DRCR.net trial is a posterior location of NV.…”

Section: Introductionmentioning

confidence: 99%

Contributory factors for developing foveal neovascularization in proliferative diabetic retinopathy

Venkatesh

Reddy

Jayadev

et al. 2022

European Journal of Ophthalmology

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Purpose Foveal neovascularisation (NV) in proliferative diabetic retinopathy (PDR) is uncommon. The study aim is to analyse a series of cases of foveal NV in PDR and ascertain the factors leading to its development. Methods In this retrospective case-control study, optical coherence tomography (OCT) and OCT-angiography (OCTA) images of PDR cases with/without foveal NV diagnosed on fluorescein angiography were analysed. Results From 124 consecutive PDR eyes, foveal NV was identified in 12 (10%) eyes. Eyes with foveal NV showed thin choroid (p = 0.001), increased FAZ area and reduced vessel density at the macula compared to control group on OCT and OCTA. After regression analysis, an increased FAZ in the superficial capillary plexus slab (p = 0.002) was associated with foveal NV development. Conclusion Our case series suggest that foveal NV is an uncommon finding, occurring due to reduced choroidal and inner retinal perfusion at the macula. Further studies are required to assess the treatment outcomes in such eyes.

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