Multimodal Evaluation of 2-D and 3-D Ultrasound, Computed Tomography and Magnetic Resonance Imaging in Measurements of the Thyroid Volume Using Universally Applicable Cross-Sectional Imaging Software: A Phantom Study

Freesmeyer, Martin; Wiegand, Steffen; Schierz, Jan-Henning; Winkens, Thomas; Licht, Katharina

doi:10.1016/j.ultrasmedbio.2014.02.013

Cited by 17 publications

(22 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Compared to a previous phantom study performed with volumes up to 200 mL and without the use of stitching [10], the present data showed even higher levels of agreement with the reference volumes -irrespective of whether the em or the mt method was used -indicating that 3D-US EFOV may be a promising option for thyroid volumetric analysis.…”

Section: Discussioncontrasting

confidence: 50%

“…In contrast, the present study focused on the feasibility of stitching 3D-US datasets specifically for thyroid volumetric analysis using ad hoc-developed phantoms. Different phantoms are available for US investigations [12,14,16,17,19] and another group also recently developed a flexible balloon phantom of the thyroid that allows for the simulation of nodular shape alterations and isthmus thickening [10]. In the present study, this original model was further adapted to increase the volume range from 200 mL to 400 mL; additionally, ventral echogenic landmarks were placed to facilitate the subsequent stitching procedure, and a support rod was added with the intent of maintaining the anthropomorphic shape of the thyroid phantom and retaining a trachea dummy in place.…”

Section: Discussionmentioning

confidence: 99%

“…A combined extended 3D-US dataset, now including the whole phantom with both lobes, was then generated and stored (fig 3e). To reduce the time effort of the subsequent volumetric analyses using mt, the extended 3D-US datasets were converted from a transverse slice thickness of 0.21-0.4 mm to a uniform thickness of 3.0 mm using PMOD software and stored again [10].…”

Section: Stitching and Post-stitching Data Modificationmentioning

confidence: 99%

“…Therefore, the aims of the present study were 1) to investigate whether stitching of two separately scanned 3D-US partial thyroid volumes is feasible and 2) to assess the accuracy of the resulting volumetric 3D-US EFOV. For this purpose, ad hoc thyroid phantoms with volume and shape variants were developed based on a previously established phantom [10].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Freesmeyer¹,

Knichel²,

Kühnel³

et al. 2018

Med Ultrason

Self Cite

View full text Add to dashboard Cite

Aims: Thyroid volume has to be measured in goiters prior to radioiodine treatment to calculate the needed amount of radioactivity. Modern clinical equipment for ultrasonography shows the trend to smaller probes, so that larger goiters do not fit any longer into the probe’s field of view. This study evaluated the feasibility and accuracy of stitching procedures applied to thyroid volumetric analysis performed using three-dimensional ultrasound (3D-US).Material and methods: Ad hoc thyroid phantoms of different shapes (regular, nodular, thickened isthmus) and volumes (ranging between 50 and 400 mL) were developed. In 15 such phantoms the left and right lobes were separately scanned, and the 3D-US datasets were then assembled (stitched) using predefined landmarks and dedicated software. Volumetric analysis was then assessed via a conventional ellipsoid model (em) and manual tracing (mt). The correlation of measured and reference volumes was determined using Pearson’s correlation coefficients and Bland and Altman limits of agreement.Results: The results showed a high level of agreement (with correlation coefficients ranging from 0.974 to 0.999) for all shapes and volumes tested, including the largest volume of 400 mL. The mt method, although more time consuming, proved superior to the em.Conclusions: Stitching-mediated thyroid volumetric analysis is accurate, and its clinical performance should be investigated in future studies

show abstract

Section: Discussioncontrasting

confidence: 50%

Section: Discussionmentioning

confidence: 99%

Section: Stitching and Post-stitching Data Modificationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Freesmeyer¹,

Knichel²,

Kühnel³

et al. 2018

Med Ultrason

Self Cite

View full text Add to dashboard Cite

show abstract

“…Also, the 124 I RAIU method allows a time-efficient PET-based organ volumetry (4). In addition, there exists the possibility of performing PET/ultrasound image fusion (5)(6)(7).…”

mentioning

confidence: 99%

Assessment of Minimum ¹²⁴I Activity Required in Uptake Measurements Before Radioiodine Therapy for Benign Thyroid Diseases

et al. 2016

Self Cite

View full text Add to dashboard Cite

This study aimed to assess a hypothetical minimum administered activity of 124 I required to achieve comparability between pretherapeutic radioiodine uptake (RAIU) measurements by 124 I PET/CT and by 131 I RAIU probe, the clinical standard. In addition, the impact of different reconstruction algorithms on 124 I RAIU and the evaluation of pixel noise as a parameter for image quality were investigated. Methods: Different scan durations were simulated by different reconstruction intervals of 600-s list-mode PET datasets (including 15 intervals up to 600 s and 5 different reconstruction algorithms: filtered-backprojection and 4 iterative techniques) acquired 30 h after administration of 1 MBq of 124 I. The Bland-Altman method was used to compare mean 124 I RAIU levels versus mean 3-MBq 131 I RAIU levels (clinical standard). The data of 37 patients with benign thyroid diseases were assessed. The impact of different reconstruction lengths on pixel noise was investigated for all 5 of the 124 I PET reconstruction algorithms. A hypothetical minimum activity was sought by means of a proportion equation, considering that the length of a reconstruction interval equates to a hypothetical activity. Results: Mean 124 I RAIU and 131 I RAIU already showed high levels of agreement for reconstruction intervals of as short as 10 s, corresponding to a hypothetical minimum activity of 0.017 MBq of 124 I. The iterative algorithms proved generally superior to the filteredbackprojection algorithm. 124 I RAIU showed a trend toward higher levels than 131 I RAIU if the influence of retrosternal tissue was not considered, which was proven to be the cause of a slight overestimation by 124 I RAIU measurement. A hypothetical minimum activity of 0.5 MBq of 124 I obtained with iterative reconstruction appeared sufficient both visually and with regard to pixel noise. Conclusion: This study confirms the potential of 124 I RAIU measurement as an alternative method for 131 I RAIU measurement in benign thyroid disease and suggests that reducing the administered activity is an option. CT information is particularly important in cases of retrosternal expansion. The results are relevant because 124 I PET/CT allows additional diagnostic means, that is, the possibility of performing fusion imaging with ultrasound. 124 I PET/CT might be an alternative, especially when hybrid 123 I SPECT/CT is not available.

show abstract

3D Ultrasound

Elaraj¹

2017

Advanced Thyroid and Parathyroid Ultrasound

View full text Add to dashboard Cite

Multimodal Evaluation of 2-D and 3-D Ultrasound, Computed Tomography and Magnetic Resonance Imaging in Measurements of the Thyroid Volume Using Universally Applicable Cross-Sectional Imaging Software: A Phantom Study

Cited by 17 publications

References 24 publications

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Assessment of Minimum ¹²⁴I Activity Required in Uptake Measurements Before Radioiodine Therapy for Benign Thyroid Diseases

3D Ultrasound

Contact Info

Product

Resources

About

Multimodal Evaluation of 2-D and 3-D Ultrasound, Computed Tomography and Magnetic Resonance Imaging in Measurements of the Thyroid Volume Using Universally Applicable Cross-Sectional Imaging Software: A Phantom Study

Cited by 17 publications

References 24 publications

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Stitching of sensor-navigated 3D ultrasound datasets for the determination of large thyroid volumes – a phantom study

Assessment of Minimum 124I Activity Required in Uptake Measurements Before Radioiodine Therapy for Benign Thyroid Diseases

3D Ultrasound

Contact Info

Product

Resources

About

Assessment of Minimum ¹²⁴I Activity Required in Uptake Measurements Before Radioiodine Therapy for Benign Thyroid Diseases