Multimodal 2D and 3D microscopic mapping of growth cartilage by computational imaging techniques – a short review including new research
Fredrik K Mürer,
Kim R Tekseth,
Basab Chattopadhyay
et al.
Abstract:Being able to image the microstructure of growth cartilage is important for understanding the onset and progression of diseases such as osteochondrosis and osteoarthritis, as well as for developing new treatments and implants. Studies of cartilage using conventional optical brightfield microscopy rely heavily on histological staining, where the added chemicals provide tissue-specific colours. Other microscopy contrast mechanisms include polarization, phase- and scattering contrast, enabling non-stained or “lab… Show more
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