Multilocus enzyme electrophoresis analysis of rapidly-growing mycobacteria: an alternative tool for identification and typing

Caierão, Juliana; Paiva, José Augusto Cardoso Dias; Sampaio, Jorge Luiz Mello; Silva, Marlei Gomes da; Santos, Debora Ribeiro de Souza; Coelho, Fábrice Santana; Fonseca, Leila de Souza; Duarte, Rafael Silva; Armstrong, Derek T; Régua-Mangia, Adriana Hamond

doi:10.1016/j.ijid.2015.11.010

Cited by 4 publications

(1 citation statement)

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“…This method allows bacteria to be differentiated based on the relative migration rate pattern of a large group of intracellular enzymes. The different patterns result from mutations in the genes coding for these enzymes, which change the amino acid sequence of the proteins (Caierão et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Towards a better understanding of the bacterial pan-genome

Gmiter

Nawrot

Pacak

et al. 2021

FBOe

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The bacterial pan-genome is a relatively new concept that refers to the number of genes observed in a given set of bacterial genome sequences, either at the intra- or inter-species level. Determining the pan-genome of a given species of bacteria using a large number of strains allows one to compare multiple genes and to determine evolutionary links between isolates. This information can help to determine population structure, diversity in terms of prevalence in a given environment and pathogenicity of microorganisms. Within this review, we explain the most important issues related to pan-genome studies. We also include a brief description of some selected bacterial pan-genomes. Finally, we propose an easy-toperform workflow to study bacterial pan-genomes that will facilitate nonexperts in a pan-genome-based investigation.

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Section: Introductionmentioning

confidence: 99%