Multifunctional phytochemical nanoplatform for comprehensive treatment of all-stage MRSA biofilm associated infection and its accompanying inflammation

Wang, Tingting; Cui, Xilong; Cai, Shuang; Zou, Xinshu; Zheng, Sidi; Li, Yanhua; Zhang, Zhiyun

doi:10.1016/j.cej.2023.147951

Cited by 1 publication

(1 citation statement)

References 42 publications

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“…Additionally, Chitosan nanoparticles adorned with rhamnolipids (RL) have been loaded with the antimicrobial phytochemical isoliquiritigenin (ISL) (isl@rl-cs). This formulation is capable of concurrently eliminating the biofilm of methicillin-resistant Staphylococcus aureus (MRSA) throughout all stages and mitigating the associated inflammation [53].…”

Section: Polymer Nanoparticlesmentioning

confidence: 99%

Novel Drug Delivery Systems: An Important Direction for Drug Innovation Research and Development

Chen,

Yang,

Liu

et al. 2024

Pharmaceutics

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The escalating demand for enhanced therapeutic efficacy and reduced adverse effects in the pharmaceutical domain has catalyzed a new frontier of innovation and research in the field of pharmacy: novel drug delivery systems. These systems are designed to address the limitations of conventional drug administration, such as abbreviated half-life, inadequate targeting, low solubility, and bioavailability. As the disciplines of pharmacy, materials science, and biomedicine continue to advance and converge, the development of efficient and safe drug delivery systems, including biopharmaceutical formulations, has garnered significant attention both domestically and internationally. This article presents an overview of the latest advancements in drug delivery systems, categorized into four primary areas: carrier-based and coupling-based targeted drug delivery systems, intelligent drug delivery systems, and drug delivery devices, based on their main objectives and methodologies. Additionally, it critically analyzes the technological bottlenecks, current research challenges, and future trends in the application of novel drug delivery systems.

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Section: Polymer Nanoparticlesmentioning

confidence: 99%