2024
DOI: 10.3389/fphar.2024.1498728
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Multifunctional nanomaterials composed entirely of active pharmaceutical ingredients for synergistically enhanced antitumor and antibacterial effects

Qi An,
Dongmei Wang,
Liang Huang
et al.

Abstract: IntroductionMultifunctional nanomaterials are emerging as promising tools for treating both cancer and bacterial infections. However, integrating dual therapeutic capabilities into a single system remains challenging. This study presents multifunctional nanoparticles (ECI-NPs) based on Epigallocatechin gallate (EGCG) oligomers, Curcumin (CUR), and Indocyanine Green (ICG) for combined cancer and bacterial treatment.MethodsECI-NPs were synthesized via oxidative coupling of EGCG, CUR, and ICG. The nanoparticles w… Show more

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