Multifunctional microchip-based distillation apparatus I - Steam distillation for formaldehyde detection

Hsu, Sheng Yen; Liu, Chan Chiung; Yang, Chia En; Fu, Lung-Ming

doi:10.1016/j.aca.2019.02.016

Cited by 22 publications

(11 citation statements)

References 63 publications

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“…As a result, they have found widespread uses in many fields nowadays, including biomedical analysis, food safety screening, drug development, and environmental monitoring [ 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Many micro-distillation systems have been proposed in recent years [ 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. Giordano et al [ 29 ] presented a gravity-assisted micro-distillation system consisting of a polydimethylsiloxane (PDMS) microchip incorporating a heating resistor, a distillation flask, a condenser, and a distillate collector.…”

Section: Introductionmentioning

confidence: 99%

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Microfluidic Distillation System for Separation of Propionic Acid in Foods

Liu

Huang

et al. 2023

Micromachines

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A microfluidic distillation system is proposed to facilitate the separation and subsequent determination of propionic acid (PA) in foods. The system comprises two main components: (1) a polymethyl methacrylate (PMMA) micro-distillation chip incorporating a micro-evaporator chamber, a sample reservoir, and a serpentine micro-condensation channel; and (2) and a DC-powered distillation module with built-in heating and cooling functions. In the distillation process, homogenized PA sample and de-ionized water are injected into the sample reservoir and micro-evaporator chamber, respectively, and the chip is then mounted on a side of the distillation module. The de-ionized water is heated by the distillation module, and the steam flows from the evaporation chamber to the sample reservoir, where it prompts the formation of PA vapor. The vapor flows through the serpentine microchannel and is condensed under the cooling effects of the distillation module to produce a PA extract solution. A small quantity of the extract is transferred to a macroscale HPLC and photodiode array (PDA) detector system, where the PA concentration is determined using a chromatographic method. The experimental results show that the microfluidic distillation system achieves a distillation (separation) efficiency of around 97% after 15 min. Moreover, in tests performed using 10 commercial baked food samples, the system achieves a limit of detection of 50 mg/L and a limit of quantitation of 96 mg/L, respectively. The practical feasibility of the proposed system is thus confirmed.

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Section: Introductionmentioning

confidence: 99%

“…Moreover, the practicality of the system was shown by quantifying the concentration of ethanol in seven alcoholic beverages. Hsu et al [ 33 ] proposed a micro-distillation system for quantifying the concentration of formaldehyde (CH 2 O) in food samples. The sample was vaporized by a steam flow and driven through a cooled condenser zone.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Distillation System for Separation of Propionic Acid in Foods

Liu

Huang

et al. 2023

Micromachines

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“…Microfluidic technology has advanced rapidly over the past decade and has resulted in the development of many lab-on-a-chip [ 2 , 3 , 4 , 5 , 6 , 7 , 8 ] and lab-on-paper [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ] platforms for total analysis systems in fields such as medicine and healthcare, environmental monitoring, cell biology, food safety inspection, and so on. Both platforms offer the advantages of cost-effectiveness, a simple operation, high reliability, high sensitivity, low sample/reagent consumption, and a near-instant on-site detection capability.…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk

Lee

Kung

et al. 2021

Micromachines

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Milk is a necessity for human life. However, it is susceptible to contamination and adulteration. Microfluidic analysis devices have attracted significant attention for the high-throughput quality inspection and contaminant analysis of milk samples in recent years. This review describes the major proposals presented in the literature for the pretreatment, contaminant detection, and quality inspection of milk samples using microfluidic lab-on-a-chip and lab-on-paper platforms in the past five years. The review focuses on the sample separation, sample extraction, and sample preconcentration/amplification steps of the pretreatment process and the determination of aflatoxins, antibiotics, drugs, melamine, and foodborne pathogens in the detection process. Recent proposals for the general quality inspection of milk samples, including the viscosity and presence of adulteration, are also discussed. The review concludes with a brief perspective on the challenges facing the future development of microfluidic devices for the analysis of milk samples in the coming years.

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“…Microfluidic devices exhibit the potential to perform high-throughput and high-efficiency biochemical detection experiments that consume minimal amounts of samples and reagents, with low detection limits. In addition to other advantages, microfluidic devices and chip detection experiments exhibit higher economic efficiency, higher portability, and simpler operations than conventional detection methods [ 17 , 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Design of an Integrated Microfluidic Paper-Based Chip and Inspection Machine for the Detection of Mercury in Food with Silver Nanoparticles

Shih

Hsieh

et al. 2021

Biosensors

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For most of the fast screening test papers for detecting Hg2+, the obtained results are qualitative. This study developed an operation for the μPAD and combined it with the chemical colorimetric method. Silver nanoparticle (AgNP) colloids were adopted as the reactive color reagent to combine and react with the Hg standards on the paper-based chip. Then, the RGB values for the color change were used to establish the standard curve (R2 > 0.99). Subsequently, this detection system was employed for the detection tests of actual samples, and the detected RGB values of the samples were substituted back to the formula to calculate the Hg2+ contents in the food. In this study, the Hg2+ content and recovery rate in commercially available packaged water and edible salts were measured. The research results indicate that a swift, economical, and simple detection method for Hg2+ content in food has been successfully developed.

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Multifunctional microchip-based distillation apparatus I - Steam distillation for formaldehyde detection

Cited by 22 publications

References 63 publications

Microfluidic Distillation System for Separation of Propionic Acid in Foods

Microfluidic Distillation System for Separation of Propionic Acid in Foods

Recent Advances in Microfluidic Devices for Contamination Detection and Quality Inspection of Milk

Design of an Integrated Microfluidic Paper-Based Chip and Inspection Machine for the Detection of Mercury in Food with Silver Nanoparticles

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