Multifunctional imine-POSS as uncommon 3D nanobuilding blocks for supramolecular hybrid materials: synthesis, structural characterization, and properties

Abstract

In this article, we report on the chemistry and the spectroscopic properties of well-defined imino-functionalized polyoctahedral oligomeric silsesquioxanes (imine-POSS) with various substitutions. Our efforts were mainly focused on side chains with sizable aryl groups possessing hydroxyl, nitro, and halide moieties. Such a choice enabled us to track their reduction abilities to secondary amine-POSS, tautomerization effects, and thermal properties. We also report for the first time the solid-state structures of five imino-functionalized cage-like octasilsesquioxanes. These structures provide unique examples of the complexities of three-dimensional packing motifs and their relationship with the assembly of tunable materials from nanobuilding blocks.

First step towards a model system of the drug delivery network based on amide-POSS nanocarriers

“…This group includes polyhedral oligomeric silsesquioxanes, which possess a three-dimensional, cage-like structure that is able to form building blocks containing an inorganic inner siloxane core. 7 In addition, external terminal groups are able to bind small drug molecules, reducing their toxicity, which may be due to the sudden discharge of large amounts of the drug to the human body, and effectively assist in controlling the release. Thanks to the fact that POSS molecules can be suitably functionalized, it is possible to specify and optimize the process of the transportation of the drug, i.e.…”

“…Here, depending on the nature of substituent, POSS species form star-like (for a phenyl group) or rod-like (for a p-halogen substituted phenyl group) structures. 7 Well-designed drug delivery systems are extremely difficult to estimate and design. This is due to the fact that there is a number of complex mechanisms that are involved in the release process of pharmacologically active compounds.…”

Introduction of Boron Functionalities into Silsesquioxanes: Novel Independent Methodologies

“…[1][2][3][4][5][6][7][8] In this connection, they have been extensively investigated, especially in materialc hemistry. [13][14][15][16][17] Traditionally,c onventional methods using halo-compounds are used to modify their structure, [18][19][20][21][22] however catalytic solutionsa re becoming increasingly investigated. [13][14][15][16][17] Traditionally,c onventional methods using halo-compounds are used to modify their structure, [18][19][20][21][22] however catalytic solutionsa re becoming increasingly investigated.…”

“…[9][10][11][12] Recently,t he synthesis of functionalizeds ilsesquioxanes cages( SQs) containing other heteroatomsa nd functional groupsh as been strongly developed by many scientists. [13][14][15][16][17] Traditionally,c onventional methods using halo-compounds are used to modify their structure, [18][19][20][21][22] however catalytic solutionsa re becoming increasingly investigated. [23][24][25][26][27][28] On the other hand, the boron modification of variousc ompounds, [29][30][31][32][33] polymers, [34,35] and nanoparticles is attractivef or aw ide range of applications.…”

Controlled formation of ordered coordination polymeric networks using silsesquioxane building blocks

“…1,2 In recent years, several efforts have been made to exploit POSS as a building block for synthesising ordered materials, and some schemes have been proposed. [3][4][5][6][7][8][9][10][11][12][13][14] As one of the most accepted schemes, POSS were first tethered with chemical moieties and then self-assembled/crosslinked to form higher-order structures via intermolecular interactions. For example, Shimojima et al synthesised porous materials by modifying POSS terminals with an alkyl group 3 or dimethylsilanol groups.…”