Multifunctional hydrogel as wound dressing for intelligent wound monitoring

Wang, Lirong; Zhou, Mengyun; Xu, Tailin; Zhang, Xueji

doi:10.1016/j.cej.2022.134625

Cited by 102 publications

(51 citation statements)

References 54 publications

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“…Hydrogel adhesion usually results from surface energy, intermolecular interactions, and near-surface effects [ 1 , 2 ]. Academic researchers have typically focused on the surface of hydrogels or the interface between hydrogels and substrates to create strong hydrogel adhesion [ 3 , 8 ]. The internal structure of hydrogel can also affect the adhesion of the hydrogel’s surface, but a few research studies have explored the relationship between the internal structure of hydrogels and surface adhesion [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Kumar

et al. 2022

Gels

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The development of adhesive hydrogel materials has brought numerous advances to biomedical engineering. Hydrogel adhesion has drawn much attention in research and applications. In this paper, the study of hydrogel adhesion is no longer limited to the surface of hydrogels. Here, the effect of the internal crosslinking degree of hydrogels prepared by different methods on hydrogel adhesion was explored to find the generality. The results show that with the increase in crosslinking degree, the hydrogel adhesion decreased significantly due to the limitation of segment mobility. Moreover, two simple strategies to improve hydrogel adhesion generated by hydrogen bonding were proposed. One was to keep the functional groups used for hydrogel adhesion and the other was to enhance the flexibility of polymer chains that make up hydrogels. We hope this study can provide another approach for improving the hydrogel adhesion generated by hydrogen bonding.

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Section: Introductionmentioning

confidence: 99%

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Kumar

et al. 2022

Gels

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“…To investigate the pH impact of initial salt solution on the adsorption of Cu(II) by hydrogels, solutions of Cu(OAc)2.H2O (10 ppm) with different pH values (2, 4, 6, 8, 10, 12 and 14) were prepared. Hydrogel (V) (0.01 g) was added to the aqueous solution of Cu(OAc)2.H2O (2 mL, 10 mg L -1 ) of varied pH values (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) and shacked for 24 h in order to achieve adsorption equilibrium at room temperature. Hydrogels were isolated by filtration and the filtrates were analyzed by ICP to determine the equilibrium concentration (Ce).…”

Section: Investigating the Effect Of Ph Of The Medium On The Adsorptionmentioning

confidence: 99%

“…biosensor [11], wound healing [12], bio-separation [13], tissue engineering [14] and environmental applications like adsorption [15]. Smart hydrogels are categorized based on the type of the stimuli that caused their swelling behavior.…”

Section: Introductionmentioning

confidence: 99%

Kinetic and Equilibrium Function and Switchable Catalytic Activity of Some Thermo-Responsive Hydrogel Metal Absorbents Based on Modified PNIPAM

Ghasemi

Owrang

Javaheri

2022

Preprint

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Synthesis and identification of some thermo-responsive hydrogel metal absorbents based on Schiff base modified PNIPAM is described. PNIPAM hydrogel is produced through conventional free-radical polymerization method. The hydrogel is amino modified with different amines and then treated with various aldehydes to make polymeric Schiff-bases supposing to utilize as an absorbent for Cu salt. Characterization of the as-prepared hydrogels was performed properly and confirmed the corresponding structures. Kinetic and equilibrium function of the absorbents and the effect of distinct variables like pH, adsorbent amount and contact time in the absorption process are investigated in detail. Kinetic and adsorption isotherm data agreed with pseudo-second order model and Langmuir isotherm, respectively. The maximum value of adsorption capacity of the prepared adsorbent was around 8550 mg g-1. In addition, the corresponding switchable catalytic activity using one of the thermo-responsive hydrogel metal absorbents in the reduction of 4-nitro phenol to 4-amino phenol in the role of model reaction is examined.

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“…In this review we concentrate on microbiology applications. Since their first description of hydrogels by Wichterle and Lím in 1960, hydrogels have been extensively used in a wide range of biomedical applications such as drug delivery, − tissue engineering, − wound dressings, − and biosensing. − Over the years, with the surge in bacterial infections associated with rapidly evolving antimicrobial resistance, the diagnostics and management of bacteria-associated infectious diseases has become challenging. Hydrogels, due to their versatility and enabling features, provide a favorable platform for a wide range of bacterial/antibacterial applications.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Composite Hydrogels for Bacterial Capture, Growth/Elimination, and Sensing Applications

Dsouza

Constantinidou

Arvanitis

et al. 2022

ACS Appl. Mater. Interfaces

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Hydrogels are cross-linked networks of hydrophilic polymer chains with a three-dimensional structure. Owing to their unique features, the application of hydrogels for bacterial/antibacterial studies and bacterial infection management has grown in importance in recent years. This trend is likely to continue due to the rise in bacterial infections and antimicrobial resistance. By exploiting their physicochemical characteristics and inherent nature, hydrogels have been developed to achieve bacterial capture and detection, bacterial growth or elimination, antibiotic delivery, or bacterial sensing. Traditionally, the development of hydrogels for bacterial/antibacterial studies has focused on achieving a single function such as antibiotic delivery, antibacterial activity, bacterial growth, or bacterial detection. However, recent studies demonstrate the fabrication of multifunctional hydrogels, where a single hydrogel is capable of performing more than one bacterial/antibacterial function, or composite hydrogels consisting of a number of single functionalized hydrogels, which exhibit bacterial/antibacterial function synergistically. In this review, we first highlight the hydrogel features critical for bacterial studies and infection management. Then, we specifically address unique hydrogel properties, their surface/network functionalization, and their mode of action for bacterial capture, adhesion/growth, antibacterial activity, and bacterial sensing, respectively. Finally, we provide insights into different strategies for developing multifunctional hydrogels and how such systems can help tackle, manage, and understand bacterial infections and antimicrobial resistance. We also note that the strategies highlighted in this review can be adapted to other cell types and are therefore likely to find applications beyond the field of microbiology.

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Multifunctional hydrogel as wound dressing for intelligent wound monitoring

Cited by 102 publications

References 54 publications

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

The Effect of Crosslinking Degree of Hydrogels on Hydrogel Adhesion

Kinetic and Equilibrium Function and Switchable Catalytic Activity of Some Thermo-Responsive Hydrogel Metal Absorbents Based on Modified PNIPAM

Multifunctional Composite Hydrogels for Bacterial Capture, Growth/Elimination, and Sensing Applications

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