Multifunctional Biocatalysts for Organic Synthesis
Thomas W. Thorpe,
James R. Marshall,
Nicholas J. Turner
Abstract:Biocatalysis is becoming an indispensable tool in organic synthesis due to high enzymatic catalytic efficiency as well as exquisite chemo-and stereoselectivity. Some biocatalysts display great promiscuity including a broad substrate scope as well as the ability to catalyze more than one type of transformation. These promiscuous activities have been applied individually to efficiently access numerous valuable target molecules. However, systems in which enzymes possessing multiple different catalytic activities … Show more
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