Multifunctional amphiphilic ionic liquid pathway to create water-based magnetic fluids and magnetically-driven mesoporous silica

Shen, Jing; He, Wen; Wang, Tongwen

doi:10.1039/c8ra10065a

Cited by 8 publications

(7 citation statements)

References 33 publications

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“…1-methylimidazole and 1-hexadecyl chloride were purchased from Acrös Organics. Long-chain ionic liquid 1-hexadecyl-3-methylimidazolium chloride (IL 16 ) was synthesized according to the original report [ 27 ]. Styrene (St) and sodium dodecylbenzene sulfonate (SDBS) were purchased from Shanghai Titan Technology Co., Shanghai, China.…”

Section: Methodsmentioning

confidence: 99%

Automatic Detoxification Medicine Delivery by Thermo-Sensitive Poly(ethylene glycol)-Based Nanogels

Shen

Meng

et al. 2022

Polymers

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During the medication-assisted treatment of drug abuse, side effects and addiction liabilities are commonly observed. Thus, control of the medication dose is very important. According to body temperature abnormalities in drug abusers, a thermo-sensitive nanogel was synthesized as a drug carrier to automatically deliver detoxification medicines. This nanogel was prepared through the synthesis of polystyrene (PS) core microspheres, followed by coverage with a nonlinear poly(ethylene glycol)-based copolymer shell. The PS core microspheres were found to be an ideal hydrophobic core for loading the detoxification medicines effectively. The nonlinear poly(ethylene glycol)-based copolymer shell layer consisted of 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) and oligo(ethylene glycol) methyl ether methacrylates (Mn = 300 g mol−1, MEO5MA). The monomer feeding molar ratio n(MEO2MA)/n(MEO5MA) of 1:3 enabled PS@P(MEO2MA-co-MEO5MA) nanogels to exhibit a distinguished colloidal stability and an adjustable volume phase transition temperature which is within the drug addicts’ abnormally fluctuating temperature range. Importantly, it was found that the obtained PS@P(MEO2MA-co-MEO5MA) nanogels displayed good biocompatibility with rat aortic endothelial cells in the given concentration range. The nanogels also exhibited a satisfactory loading efficiency and thermo-sensitive/sustained release characteristics for three detoxification medicines: sinomenine, diltiazem and chlorpromazine.

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Section: Methodsmentioning

confidence: 99%

Automatic Detoxification Medicine Delivery by Thermo-Sensitive Poly(ethylene glycol)-Based Nanogels

Shen

Meng

et al. 2022

Polymers

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“…One PS, n ‐hexadecylpyridinium chloride, C 16 PyrCl (Sigma‐Aldrich, São Paulo, Brazil), and seven ISs were used in this study: 1‐ n ‐decyl‐3‐methylimidazolium chloride, C 10 MlmCl (Sigma‐Aldrich); 1‐ n ‐hexadecyl‐3‐methylimidazolium chloride, C 16 MlmCl (Shen et al, 2019); 1,3‐di‐ n ‐decyl‐2‐methylimidazolium chloride (C 10 ) 2 MImCl (Sigma‐Aldrich); 1‐ n ‐butyl‐3‐methylimidazolium chloride, C 4 MlmCl (Sigma‐Aldrich); 1‐ n ‐hexadecyl‐3‐methylimidazolium methanesulfonate, C 16 MlmMeS (Pilz‐Junior et al, 2019); 1,3‐di‐ n ‐hexadecylimidazolium chloride, (C 16 ) 2 lmCl (Rohini et al, 2013); and 1‐ n ‐octadecyl‐3‐methylimidazolium chloride, C 18 MlmCl (CJC China Jie Chemical, Shanghai, China) (Figure 1). Solutions were prepared in sterile distilled water, at a concentration of 100 μg ml −1 (0.01%), and they were sterilized with 0.22 μm pore filters, and kept in sterilized bottles until use.…”

Section: Methodsmentioning

confidence: 99%

Impact of imidazolium salts to reduce the infection of Bombyx mori caterpillars by Beauveria bassiana

Pessini

Schrekker

Silva

et al. 2022

Entomologia Exp Applicata

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Sericulture in Brazil is an activity developed mainly by families on small rural properties, contributing to improving workers' income and reducing rural exodus (Meng et al., 2017). This configures a low technological level for the breeding environment of silkworm, Bombyx mori L. (Lepidoptera: Bombycidae), and among the problems associated with sericulture that directly affect the quality of the threads, the diseases caused by entomopathogenic viruses, bacteria, and fungi stand out (

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“…2‐(2‐methoxyethoxy)ethyl methacrylate (MEO 2 MA, 95%), oligo(ethylene glycol)methyl ether methacrylate (MEO 5 MA ( M n = 300 g mol −1 ), and poly(ethylene glycol) dimethacrylate (PEGDMA, M n = 550 g mol −1 , crosslinker) were purified with neutral Al 2 O 3 . Amphiphilic ionic liquid, 1‐hexadecyl‐3‐methylimidazolium chloride (abbreviated as AIL 16 ) was prepared and identified according to a route reported in the literature 17 . Methylmethacrylate (MMA), sodium dodecyl sulfate (SDS), potassium persulfate (K 2 S 2 O 8 ), and 2,2′‐azobis(2‐methylpropionamidine) dihydrochloride (AAPH) were used as received.…”

Section: Methodsmentioning

confidence: 99%

ThermosensitivePMMAcore/oligo(ethylene glycol)‐based shell microgels as drug carriers in detoxification treatment

Meng

Shen

et al. 2021

J of Applied Polymer Sci

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The core‐shell structured polymer microgels were synthesized by coating the hydrophobic poly(methyl methacrylate) (PMMA) sphere cores with hydrophilic nonlinear poly(ethylene glycol)‐based gel shell layer. The uniqueness of these core‐shell microgels lies in the integration of the PMMA core microsphere with strong hydrophobicity and the novel oligo(ethylene glycol)‐based gel layer with well‐defined thermosensitivity for improving loading/release efficacy of two detoxification drugs (chlorpromazine and diltiazem). The hydrophilic shell is composed of hydrophilic copolymer of 2‐(2‐methoxyethoxy)ethyl methacrylate (MEO2MA) with oligo(ethylene glycol) methyl ether methacrylates (MEO5MA). It was found that the molar ratio of two shell monomers n(MEO2MA)/n(MEO5MA) of 1:6 was an ideal matching value for production of the P(MEO2MA)/P(MEO2MA‐co‐MEO5MA) core‐shell microgels with tunable volume phase transition temperature and excellent colloidal stability across the physiologically important temperature range. Moreover, chlorpromazine‐ and diltiazem‐loaded microgels can show an obvious thermosensitive release and in vitro sustained‐release characteristic up to 80 h.

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Multifunctional amphiphilic ionic liquid pathway to create water-based magnetic fluids and magnetically-driven mesoporous silica

Abstract: 1-Alkyl-3-methylimidazolium chloride (CnmimCl) can be used to construct bilayer CnmimCl stabilized magnetic fluids, and subsequently magnetic mesoporous silica can be prepared by using the C16mimCl as template in the magnetic fluids.

Cited by 8 publications

References 33 publications

Automatic Detoxification Medicine Delivery by Thermo-Sensitive Poly(ethylene glycol)-Based Nanogels

Automatic Detoxification Medicine Delivery by Thermo-Sensitive Poly(ethylene glycol)-Based Nanogels

Impact of imidazolium salts to reduce the infection of Bombyx mori caterpillars by Beauveria bassiana

ThermosensitivePMMAcore/oligo(ethylene glycol)‐based shell microgels as drug carriers in detoxification treatment

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