Multifocal Retroperitoneal Sarcoma

Abstract

Introduction. Retroperitoneal sarcomas comprise a small proportion of all soft tissue sarcomas, and multiple factors influence their clinical behavior. Histopathological type and grade as well as complete surgical resection especially on the first operative attempt are well recognized as the main prognostic factors. Multifocality is another prognostic factor, which compromises therapy and finally makes prognosis worse due to multiple adverse implications. Case Presentation. A rare case of a 65-year-old male patient suffering from a multifocal retroperitoneal liposarcoma successfully treated in our hospital is presented herein. Discussion. Also, general considerations for these tumors are discussed, and especially multifocality is underlined as an ominous sign of retroperitoneal sarcomas behavior. Despite multifocality, once again complete surgical excision remains the mainstay of treatment of these patients, as long as further systemic and local therapies do not provide durable results.

Coincident retroperitoneal and sigmoid colon liposarcoma: A rare occurrence

“…Rarely, neurological findings due to mass pressure, may accompany [6]. Metastasis may be detected in approximately 11% of the patients and metastases are frequently occur in lungs and liver [6]. Despite admitting in later period, no distant metastases were detected in the patient.…”

“…In our case, the present symptoms were recognized in later period and the patient was admitted with a big mass. Rarely, neurological findings due to mass pressure, may accompany [6]. Metastasis may be detected in approximately 11% of the patients and metastases are frequently occur in lungs and liver [6].…”

“…Abdominal computed tomography (CT) scan and MRI scan may show the association of the mass with adjacent organs and vascular structures, and may provide information about histological type. There are publications recommending abdominal CT scan or MRI scan as ideal method [6][7][8]. In our case, the structure of mass and its association with surrounding tissues and adjacent organs were assessed in detail before the operation with MRI.…”

“…In our day, the only treatment for retroperitoneal liposarcomas is en bloc R0 resection [2,5,6,9]. There is not enough evidence regarding radiotherapy and chemotherapy modalities [2,5,6,9]. The most important prognostic factors are R0 resection and tumor histology [3,9].…”

“…The most important prognostic factors are R0 resection and tumor histology [3,9]. Multifocality is a rare but important prognostic parameter [6].…”