Multifocal Osteonecrosis Glucocorticoid Induced

Postoperative manifestations like pain, edema, affected oral functions provoke transitory morbidity in patients to a late recovery. Various classes of medicines are prescribed to prevent placing patients in such unpleasant situations. Both dexamethasone and methylprednisole can be used to reduce the manifestations of the postoperative disease. Although the state of local inflammation is precursory to healing, its exacerbation can lead to extremely painful severe local edema through tissue distention. In the initial phase of the inflammatory process, glucocorticoids act as producers of vein-active substances like prostaglandins and leukins, as dexamethasone has a recognised capacity of reducing COX-2, which is responsible for generating PGs which are produced within the inflammatory response. The efficiency of glucocorticoids is admitted in reducing the inflammatory state, lying at the top of oral maxillofacial surgeons�s choice in the therapy of postoperative manifestations. Our research was addressed to a lot of 68 patients to whom we performed interventions of oral and maxillofacial surgery at the Outpatient Clinic of Oral-Maxillofacial Surgery of Ia�i. Dexamethasone is a strong glucocorticoid with the following chemical formula: 90-fluoral-160 methylprednisole. The antiinflamatory effect of a 0.75 mg dosis of dexamethasone is equivalent to that produced by 5 mg of Prednison. Dexamethasone is more efficient than Medrol in the treatment of postoperative edema with complete remission of symptomatology.

mentioning

confidence: 99%

Glucocorticoids and Postoperative Disease in Oral - Maxillofacial Surgery

Budacu¹,

Cioranu²,

Chiscop³

et al. 2017

“…The exothermic reaction during polymerization produces 12-14 kcal / 100g of bone cement [20]. Significant quantities of cement (about 50-60 g) can reach temperatures of 70-80 degrees Celsius, but in vivo, the capacity of the prosthetic components to absorb heat [21], as well as the adjacent circulation, the local temperature does not exceed 39-42 degrees Celsius, for a short time, to a thickness of up to 5 mm of cement [22] (figs. 7-9).…”

Section: Experimental Partmentioning

confidence: 99%

Aspects of Cementation in Shoulder Hemiarthroplasty after Complex Fracture of the Proximal Humerus

Turcu¹,

Moga²,

Barbilian³

2018

The first uses of the polymers at the articular level were: joint components, cement fixation of prosthetic components at the bone, and sutures of tendons and ligaments. Since 1970, when polymethyl methacrylate (PMMA) was introduced, bone cement is the choice of choice to fix the prosthetic implant to bone. The cementation of the implant components is a commonly used procedure for hip, knee and shoulder arthroplasty: the femoral stem and the acetabular cup (in the case of total hip arthroplasty), the femoral and tibial components (in the case of total knee arthroplasty), the humeral stem (in hemiarthroplasty, total arthroplasty: anatomical or arthroplasty with inverse shoulder prosthesis) The objectives of this study are to establish the optimal indication of the cementing process, to evaluate and compare the results of cemented hemiarthroplasty, the real benefit from the immediate postoperative functional recovery program, for elderly patients with a diminished bone stock with complex fractures of proximal humerus. The success of the surgical treatment for complex fractures of proximal humerus depends to a large extent on establishing a correct diagnosis, an optimal surgical indication, a thorough preoperative planning, an optimal implant, a periarticular soft tissue reconstruction, and an effective postoperative recovery program.

“…To prevent and reduce the intensity of radiodermatitis, moisturizing creams, topical corticosteroids, proteolytic enzymes, zinc or silver sulfadiazine are used but there is no consensus on the recommended standard [15][16][17][18][19].…”

mentioning

confidence: 99%

Use of Gentian Violet in the Treatment of Severe Radiodermatitis Secondary to Adjuvant Radiotherapy in Breast Cancer

Munteanu¹,

Condorovici²,

Patrascu³

et al. 2017

Self Cite

Adjuvant radiotherapy is indicated for patients with conservatively or radically operated breast cancer, demonstrating the benefit of this type of treatment for local recurrence rate and survival. Radiodermatitis are radiation-induced skin reactions, a significant side effect of cumulative ionizing radiation in significant doses at the skin level during the treatment of various tumor localizations. This study presents aspects regarding prevention and treatment of radiodermatitis in patients with adjuvant irradiated breast cancer treated in the Regional Institute of Oncology Iasi. In the study group, use of gentian violet has helped to alleviate these side effects of irradiation, both in intensity and duration, with an important impact on the quality of life of the patients.