Multifocal Osteonecrosis After Short-Term High-Dose Corticosteroid Therapy

Osteonecrosis during the treatment of childhood acute lymphoblastic leukemia: A prospective MRI study

“…The lesions did not markedly involve subarticular regions or cause cartilaginous abnormalities, which might explain their good outcome. Osteonecroses are often multifocal, but the femoral head is usually the most symptomatic site and often requires surgical treatment [39][40][41]. It is a general opinion that osteonecrosis, especially in the femoral head, should be diagnosed at an early stage, when surgical procedures may still prevent disease progression.…”

Osteonecrosis following Alcohol, Cocaine, and Steroid Use

“…(Color figure available online.) (5). In our case, the total hydrocortisone dose was 2600 mg over 13 days, which may contribute to osteonecrosis development.…”

Case Report: Multifocal Subchondral Stress Fractures of the Femoral Heads and Tibial Condyles in a Young Military Recruit

“…Osteonecrosis occurs most commonly in the hip and greater than 50% of patients have bilateral osteonecrosis [2]. Multifocal involvement of osteonecrosis also has been reported in approximately 3% of these patients [2,10,12,17]. Because the incidence of bilateral subchondral stress fractures of the femoral head is rare and multifocal involvement has not been reported, multifocal subchondral stress fractures can be easily confused with multifocal osteonecrosis.…”