Multifocal Electroretinogram in Keratoconus Patients without and with Scleral Lenses

Amorim‐de‐Sousa, Ana; Macedo-de-Araújo, Rute J.; Fernandes, Paulo; Queirós, António; González-Meijóme, José Manuel

doi:10.1080/02713683.2021.1912781

Current Eye Research

2021

DOI: 10.1080/02713683.2021.1912781

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Multifocal Electroretinogram in Keratoconus Patients without and with Scleral Lenses

Ana Amorim‐de‐Sousa

Rute J. Macedo-de-Araújo

Paulo Fernandes

et al.

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Cited by 2 publications

References 41 publications

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How Can We Best Measure the Performance of Scleral Lenses? Current Insights

Macedo-de-Araújo¹,

Fadel²,

Barnett³

2022

OPTO

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Scleral lenses (SLs) present several unique advantageous characteristics for patients. As these lenses are mainly fitted in severely diseased eyes, a thorough evaluation of the ocular surface before and after SL fitting and the on-eye SL fitting evaluation are essential and help minimize potential physiological complications. This review will explore the current and emerging techniques and instrumentation to best measure SL performance ensuring optimal lens fitting, visual quality, comfort and physiological responses, highlighting some potential complications and follow-up recommendations. A single physician could perform the great majority of evaluations. Still, the authors consider that the assessment of SL fitting should be a collaborative and multidisciplinary job, involving contact lens practitioners, ophthalmologists and the industry. This publication has reviewed the most up-to-date work and listed the most used techniques; however, the authors encourage the development of more evidence-based recommendations for SL clinical practice.

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How Can We Best Measure the Performance of Scleral Lenses? Current Insights

Macedo-de-Araújo¹,

Fadel²,

Barnett³

2022

OPTO

Self Cite

View full text Add to dashboard Cite

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Assessment of the Human Retinal Neural Selectivity to Square Gratings’ Orientation with the Multifocal and Pattern Electroretinograms

et al. 2023

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The retinal response to particular orientations might start a signaling cascade of events that help to modulate eye growth and respond to myopia control treatments. The purpose of this study was to investigate the retinal electrical activity in response to grids of different spatial orientations. The multifocal (mfERG) and pattern (PERG) ERG responses of nine eyes (spherical equivalent of −0.45 ± 1.15 D; mean age of 32.9 ± 7.7 years) were recorded with four grids (1.2 cpd) oriented at 60°, 90°, 120° and 180° under pupils’ dilation. The mfERG was analyzed by retinal eccentricity, quadrants and meridians with the same orientation of the grids. The response density of mfERG, the amplitudes of PERG and the implicit times of each peak from both tests were analyzed. The grid’s orientation did not evoke different implicit times in both tests. All retinal meridians showed higher response density with grids of parallel orientation to the meridian and lower response density with perpendicularly oriented grids. These differences were statistically significant in the horizontal and 60° meridians (p < 0.050). PERG response did not change with the grids’ orientations. The mfERG was sensitive to detect changes in the outer retinal activity with variations in stimulus orientation. The paradigm of meridional analysis of mfERG results might be more sensitive to orientation changes than the traditional analysis by rings, quadrants or hemifields.

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Multifocal Electroretinogram in Keratoconus Patients without and with Scleral Lenses

Cited by 2 publications

References 41 publications

How Can We Best Measure the Performance of Scleral Lenses? Current Insights

How Can We Best Measure the Performance of Scleral Lenses? Current Insights

Assessment of the Human Retinal Neural Selectivity to Square Gratings’ Orientation with the Multifocal and Pattern Electroretinograms

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