Multienergy element‐resolved cone beam CT (MEER‐CBCT) realized on a conventional CBCT platform

Abstract

We proposed a novel MEER-CBCT framework realized on a clinical CBCT platform. Simulation and experimental studies demonstrated its capability to simultaneously reconstruct x-ray attenuation coefficient, rED, and EC images accurately.

Simultaneous Image Reconstruction and Element Decomposition for Iodine Contrast Agent Visualization in Multienergy Element-Resolved Cone Beam CT

“…The image reconstruction model generally followed that in our previous study (14). In this study, we converted the model into a convex form to make it numerically more tractable.…”

“…In our previous study, Shen et al (14) successfully controlled the CBCT platform on a commonly used LINAC to realize multienergy CBCT data acquisition via the kVp switching scheme, i.e., taking x-ray projections with the kVp level cycling through different levels among projections. To address the undersampling problem caused by the kVp switching, they also developed a multi-energy element-resolved (MEER) CBCT framework to simultaneously reconstruct CBCT images at different kVp levels, as well as electron density map and the maps of a few major chemical elements.…”

“…The contributions of this study are twofold. First, on the algorithm side, we extended the previous MEER-CBCT reconstruction algorithm Shen et al (14) to include iodinerelated materials in the dictionary of the algorithm, which allowed us to handle the image reconstruction problem in the presence of the iodine contrast agent. We further converted the nonconvex optimization model in our previous study (14) into a convex form, making it easier and more efficient to solve the problem.…”

“…First, on the algorithm side, we extended the previous MEER-CBCT reconstruction algorithm Shen et al (14) to include iodinerelated materials in the dictionary of the algorithm, which allowed us to handle the image reconstruction problem in the presence of the iodine contrast agent. We further converted the nonconvex optimization model in our previous study (14) into a convex form, making it easier and more efficient to solve the problem. Second, we also performed comprehensive simulation and experimental studies to quantitatively determine the lowest possible contrast agent concentration level identifiable in MEER-CBCT images to demonstrate the potential feasibility of this method for iodine contrast imaging.…”

A prior image constraint robust principal component analysis reconstruction method for sparse segmental multi-energy computed tomography

“…Nowadays, four DECT configurations have been commercially used: dual-energy scans (3), dual-sources technique (4), dual-layer detector technique (5) and rapid kVp switching technique (6,7). The DECT has proven to be a promising application in medical imaging with the ability of material differentiation, chemical composition analysis, automatic subtraction, and pseudo-monochromatic imaging (5,(8)(9)(10).…”