Multidisciplinary Rehabilitation after Hyaluronic Acid Injections for Elderly with Knee, Hip, Shoulder, and Temporomandibular Joint Osteoarthritis

Abstract

Osteoarthritis (OA) is a prevalent degenerative joint condition characterized by cartilage deterioration, joint inflammation, and functional limitations, particularly impacting the elderly population. Rehabilitation and hyaluronic acid (HA) injections are common therapeutic approaches routinely used in clinical practice, but their synergistic potential is far from being fully characterized. Thus, the aim of this narrative review was to elucidate the multilevel benefits and synergies of integrating these two approaches in multidisciplinary OA rehabilitation. This narrative review follows the scale for the assessment of narrative review articles (SANRA) criteria and involves a comprehensive literature search from July to August 2023. Two independent reviewers screened studies, including those involving human subjects with OA, rehabilitation strategies, and outcomes following HA injection, published in English. Results: HA injections might improve joint biomechanics, reducing friction, absorbing shocks, and potentially regulating inflammation. Rehabilitation plays a pivotal role in strengthening muscles, increasing the range of motion, and enhancing overall function. Optimizing rehabilitation following HA injection might provide additional benefits in joint health. OA management requires a multidisciplinary approach integrating HA injections, rehabilitation, and personalized care. Challenges in patient adherence and healthcare resources currently exist, but emerging technologies offer opportunities to enhance patient engagement and monitoring optimizing sustainability and outcomes of patients with knee, hip, shoulder, and temporomandibular joint OA.

The Importance of Hyaluronic Acid in Biological Systems

“…Personalized patient-centered strategies, caregiver involvement, and sustainability of multidisciplinary programs are crucial. Virtual reality and augmented reality systems can provide immersive experiences, while future research should explore the synergy of HA injections in multidisciplinary care (Lippi et al, 2023). HA, a biodegradable, biocompatible, nontoxic, and nonimmunogenic polysaccharide, is widely used in medical applications like OA surgery, ocular surgery, plastic surgery, and drug delivery, particularly for target-specific, longacting therapeutics (Sudha & Rose, 2014).…”

Aesthetic Rehabilitation Medicine: Enhancing Wellbeing beyond Functional Recovery

“…Hyaluronic acid (HA) is a non-sulphated glycosaminoglycan constituted by a repetition of polymeric disaccharides of D-glucuronic acid and N-acetyl-D-glucosamine linked via glycoside bonds in an alternating fashion of β-(1 → 4) and β-(1→ 3) [89,90].…”

Network Pharmacology and Molecular Docking Study of the Chinese Miao Medicine LiuYueHuanYang in the Treatment Of Osteoarthritis

“…Currently, there are two views on the treatment of osteoarthritis: one is that osteoarthritis is di cult to cure and its course is irreversible. Osteoarthritis can only be treated with oral non-steroidal antiin ammatory drugs (NSAIDs), glucocorticosteroids, amino acid dextrose or intra-articular injections of lubricating uids such as hyaluronic acid, combined with oral Chinese medicine, local treatments and traditional Chinese medicine (TCM) physiotherapy to relieve the patient's pain symptoms (Lippi, et al,2023). None of these can restore cartilage or stop the onset of OA.…”