Abstract:First described by Cordon in 1767, aplasia cutis congenita (ACC) is characterized by the complete or partial absence of skin at birth. 1 ACC has an estimated annual incidence of 1 in 10 000 live births.Affected patients present with translucent, well-demarcated, ulcerated areas devoid of various tissue components, which can include the epidermis, dermis, subcutaneous tissue, and bone. 2 ACC occurs along the scalp vertex in 85% of cases. 2,3 To date, the etiology of ACC is unclear and appears to be multifactori… Show more
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