Multidisciplinary Approach to Wilms' Tumor: 10 Years Experience of NCI, Egypt

Sidhom, Iman; Hussien, Hesham; Kotb, Magd A.; Anwer, G.; Naga, S. Aboul; Amin, Magdy A.; Ebied, E.; Ahmed, H.

doi:10.1200/jco.2004.22.90140.8544

Cited by 2 publications

(3 citation statements)

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“…The 5‐year EFS and overall survival in our series are 77.4% and 79%, respectively. These results are equal to those reported in some series in developing countries where the 5‐year EFS is around 70% 5–8. Those results are believed to be mainly due to the multidisciplinary management of patients.…”

Section: Discussionsupporting

confidence: 62%

“…A multidisciplinary approach to the treatment of Wilms tumor has contributed significantly to these results. There are few reports of the management of Wilms tumor in developing countries 5–8, where it represents a major challenge for pediatric oncologists. Morocco is a developing country with 30 million inhabitants, of whom 36% are less than 15 years old.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of Wilms tumor according to SIOP 9 protocol in Casablanca, Morocco

Madani

Zafad

Harif

et al. 2005

Pediatric Blood & Cancer

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Section: Discussionsupporting

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Treatment of Wilms tumor according to SIOP 9 protocol in Casablanca, Morocco

Madani

Zafad

Harif

et al. 2005

Pediatric Blood & Cancer

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“…The 1-year event free and overall survival in those who took more than average cycles of chemotherapy were between and between 20% and 40% and 35% and 50% respectively. Findings were similar to other African studies where the 8-months overall survival was nearly 40%, [12] except in Sudan where their OS was 11% [13]. However, it has still been less than that of western countries where survival is greater than 90%.…”

Section: Discussionsupporting

confidence: 86%

Survival Outcome of Wilms Tumor with Multi-Modality Treatment at Jimma Hospital, Southwest Ethiopia

Birara,

Messele,

Abera

et al. 2023

OJU

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Background: Wilms' tumor (WT), the most common malignant neoplasm of the urinary tract of children [1], accounts for 5.9% of childhood cancers and affects one in every 10,000 children worldwide before the age of 15 years. The care of children with Wilm's tumor in sub-Saharan Africa is compromised due to resource deficiencies that range from inadequate healthcare budgets to paucity of appropriately trained personnel. Childhood Wilms tumor is surging as an important paediatric problem in developing and sub-Saharan Africa countries. The objective of the study is to establish an understanding on the treatment challenges and outcomes of Wilm's tumor in South West Ethiopia. Results: Forty-three Wilm's tumor patients who were admitted from January 2017 to December 2021 were included in the study. The most frequent presentation was painless abdominal swelling in 40 (93%) patients. Fourteen patients (32.6%) were hypertensive at the time of diagnosis and the other 13 (30.2%) were normal. In abdominal examination, 31 (72.1%) patients had abdominal mass not crossing the midline and 12 (27.9%) had mass crossing the midline. After multimodal treatment, 37.5% had improvement, 11.6% came back with relapse. Most patients (41.7%) abandoned treatment and 9.3% of the cohort died in the course of treatment. Conclusion: The outcomes in the treatment of Wilms Tumor have been found to be poor in this review. The main reason for poor outcome has been not receiving adequate chemotherapy after surgery. Doses of chemotherapy received after surgery significantly affected treatment outcomes (p = 0.026).

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Multidisciplinary Approach to Wilms' Tumor: 10 Years Experience of NCI, Egypt

Cited by 2 publications

References 0 publications

Treatment of Wilms tumor according to SIOP 9 protocol in Casablanca, Morocco

Treatment of Wilms tumor according to SIOP 9 protocol in Casablanca, Morocco

Survival Outcome of Wilms Tumor with Multi-Modality Treatment at Jimma Hospital, Southwest Ethiopia

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