Multidisciplinary Approach to Multiple Multiresistant Agent Infection of Instrumented Spine Surgery

Abstract

Case:We report the case of a patient with consecutive infections with several multidrug-resistant agents—including carbapenem-resistant strains of Klebsiella pneumoniae among others—from a surgical wound infection after lumbar spine fusion, only successfully treated after the resort to novel antibiotics (ceftazidime-avibactam) in combination therapy.Conclusions:Multidrug resistance has become a major challenge in today’s medicine. Care should be taken to avoid their emergence, but when present, a multidisciplinary approach is mandatory to ensure clinically up-to-date treatment choices. Multimodal antibiotic schemes tend to show the most promising results, with which successful infection resolution can still be achieved.