Multidetector Row Computed Tomography(MDCT) Evaluation of Bronchogenic Carcinoma and Histopathological Correlation

Abstract

Bronchogenic carcinoma is one among the leading causes of death in males in India and globally. Multidetector row Computed Tomography is a non-invasive technique for evaluation of bronchogenic carcinoma. Aims and objections: To document imaging characteristics of various histopathological cell types of bronchogenic carcinoma by MDCT and to correlate with histopathology. A prospective study was done on 60 patients with clinical or radiological suspicion of bronchogenic carcinoma undergoing MDCT. The final diagnosis was established by histopathology. Study duration was for 2 years from January 2013 to December 2014. Results: MDCT is a promising tool in evaluation of bronchogenic carcinoma. Squamous cell carcinoma is the most common histological celltype, closely followed by adenocarcinoma. Hilar mass was the predominant presentation followed by lung mass.

Of multidetector computed tomography (MDCT) in evaluation of lung nodule with histopathological correlation

“…Similar findings were seen in study done by Ahmed et al 6 (45 % right, 31 % left lung), Mundal et al 11 (72 % right, 52 % left lung) and Saha et al 9 Fifty-eight percent of nodules had peripheral location while 42 % were located centrally. This is in concordance with the study done by Adaikkalavan et al, 16 Biswas et al, 17 Narayanswami et al 8 Maximum lung nodules in this study were more than 7 cm in size. This suggest that most of the lung nodules express symptoms in patient in their later stages of life, when the size of the lung nodule have already In presented study, 31 % of patients were non-smokers, and 69 % were smokers.…”

“…High level of association between smoking and occurrence of lung nodules was observed. Similar findings were seen in study done by Meena et al, 5 Narayan et al, 8 where 71.36 % and 65 % patients were smokers, respectively. The most common presentation of patient was cough with expectoration.…”

“…In this study mean age of the patients was in concordance with study by Gangopadhyay et al, 4 Dharmaraj et al, 5 Ahmed et al, 6 Gupta et al, 7 Indiranarayan et al, 8 Saha et al, 9 Singh et al, 10 while it was contrary to study done by Mundal et al 11 and Mukherjee et al 12 In the present study there were 75 % male patients out of 100 patient. That result is similar to findings of Gangopadhyay et al, 4 Gadodiya et al 13 and Saha et al, 9 while in some studies 5,7,8 the preponderance is very high ie more than 80 % were male patients. In this study 61 % of males and 92 % of females were smokers.…”

“…The most common histopathological subtype was adenocarcinoma which accounted for 41 % cases. This is in concordance with studies done by Shad et al, 19 Modi et al, 20 Babu et al, 21 Gangopadhyay et al 4 that showed that there was an increasing trend in the incidence of adenoma, contrary to the studies done by Adaikkalavan et al, 16 Rawat et al, 15 Saha et al, 9 Ahmed et al, 6 Narayan et al 8 In all these studies squamous cell carcinoma was the most predominant subtype. Adenocarcinoma was seen more at peripheral location (56.84 %), than central (19.04 %).…”

Staging of Bronchogenic Carcinoma at Tertiary Health Care Centre with Multidetector Computed Tomography and Histopathological Correlation

“…Multi Detector Computed Tomography has a high positive predictive value suggestive of great diagnostic accuracy in the 80%) patients were in the 60 to 69 years age group while age group 50 to 59 years constituting 26 (31.71%) patients and 70 to 79 years constituting 13 (15.85%) of patients. This is concordance with study by Saket RK et al1 (2016) and Hathila N et al2 (2016) this study is contrary to study done by Narayanswamy I et al3 (2015) Yadav D et al4 (2016) and Dr. Babu S et al5 (2016). Male to female ratio is 4.85:1 in our study which is similar to…”