Multicriterial CNN based beam generation for robotic radiosurgery of the prostate

Abstract

Although robotic radiosurgery offers a flexible arrangement of treatment beams, generating treatment plans is computationally challenging and a time consuming process for the planner. Furthermore, different clinical goals have to be considered during planning and generally different sets of beams correspond to different clinical goals. Typically, candidate beams sampled from a randomized heuristic form the basis for treatment planning. We propose a new approach to generate candidate beams based on deep learning using radiological features as well as the desired constraints. We demonstrate that candidate beams generated for specific clinical goals can improve treatment plan quality. Furthermore, we compare two approaches to include information about constraints in the prediction. Our results show that CNN generated beams can improve treatment plan quality for different clinical goals, increasing coverage from 91.2 to 96.8% for 3,000 candidate beams on average. When including the clinical goal in the training, coverage is improved by 1.1% points.

Comparing Multi-Objective Local Search Algorithms for the Beam Angle Selection Problem

“…They argue that they can predict the influence of a candidate beam on the delivered dose individually and let this prediction guide the selection of candidate beams [43]. The same authors extend their approach to multiple criteria in [44].…”

“…(d) Cumulative hypervolume for all algorithms for semi-random initial BACs (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29). (e) Hypervolume for all algorithms for random initial BACs (30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44). (f) Cumulative hypervolume for all algorithms for random initial BACs (30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44).…”

“…(e) Hypervolume for all algorithms for random initial BACs (30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44). (f) Cumulative hypervolume for all algorithms for random initial BACs (30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44).…”