Multicore fiber with integrated fiber Bragg gratings for background-free Raman sensing

Dochow, Sebastian; Latka, Ines; Becker, Martin; Spittel, Ron; Kobelke, Jens; Schuster, Kay; Graf, A.; Brückner, Sven; Unger, Sonja; Rothhardt, Manfred; Dietzek, Benjamin; Krafft, Christoph; Popp, Jürgen

doi:10.1364/oe.20.020156

Cited by 54 publications

(39 citation statements)

References 31 publications

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“…The group led by Jürgen Popp has made these filters more effective and more convenient by inscribing Bragg gratings directly into the delivery and collection fibers see Figure 32(d) [433]. As Bragg gratings are more effective in single mode fibers, this probe collected Raman scattered light by a bundle of multicore single-mode fibers.…”

Section: Challengesmentioning

confidence: 99%

See 1 more Smart Citation

Raman spectroscopy: techniques and applications in the life sciences

Shipp¹,

Sinjab²,

Notingher³

2017

Adv. Opt. Photon.

255

189

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Raman spectroscopy is an increasingly popular technique in many areas including biology and medicine.It is based on Raman scattering, a phenomenon in which incident photons lose or gain energy via interactions with vibrating molecules in a sample. These energy shifts can be used to obtain information regarding molecular composition of the sample with very high accuracy. Applications of Raman spectroscopy in the life sciences have included quantification of biomolecules, hyperspectral molecular imaging of cells and tissue, medical diagnosis, and others. This review briefly presents the physical origin of Raman scattering explaining the key classical and quantum mechanical concepts. Variations of the Raman effect will also be considered, including resonance, coherent, and enhanced Raman scattering. We discuss the molecular origins of prominent bands often found in the Raman spectra of biological samples. Finally, we examine several variations of Raman spectroscopy techniques in practice, looking at their applications, strengths, and challenges. This review is intended to be a starting resource for scientists new to Raman spectroscopy, providing theoretical background and practical examples as the foundation for further study and exploration.

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Section: Challengesmentioning

confidence: 99%

“…This leads to [421]. (d) Fiber bundle for Raman spectroscopy created by the group led by Jürgen Popp [433]. Excitation light is delivered by the multimode fiber in the center.…”

Section: Challengesmentioning

confidence: 99%

Raman spectroscopy: techniques and applications in the life sciences

Shipp¹,

Sinjab²,

Notingher³

2017

Adv. Opt. Photon.

255

189

View full text Add to dashboard Cite

show abstract

“…A Raman probe was built consisting of one excitation fibre and six multicore single-mode fibers (19 cores) with inscribed FBGs as collection fibres. 46 …”

Section: Fibre Backgroundmentioning

confidence: 99%

“…The group of Popp has designed a probe using integrated fibre Bragg gratings and multiple multicore single mode fibres in the collection that could potentially be disposable, as these fibres can eventually be cheaply made without the requirement of relatively expensive additional optical filter components. 46 Alternatively, our own research group has developed a probe of fused silica fibres inside of a single use hypodermic needle tip which connects to a reusable probe body where the expensive optics are located. 50 …”

Section: Dealing With Biological Contaminationsmentioning

confidence: 99%

Developing fibre optic Raman probes for applications in clinical spectroscopy

et al. 2016

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Raman spectroscopy has been shown by various groups over the last two decades to have significant capability in discriminating disease states in bodily fluids, cells and tissues. Recent development in instrumentation, optics and manufacturing approaches has facilitated the design and demonstration of various novel in vivo probes, which have applicability for myriad of applications. This review focusses on key considerations and recommendations for application specific clinical Raman probe design and construction. Raman probes can be utilised as clinical tools able to provide rapid, non-invasive, real-time molecular analysis of disease specific changes in tissues. Clearly the target tissue location, the significiance of spectral changes with disease and the possible access routes to the region of interest will vary for each clinical application considered. This review provides insight into design and construction considerations, including suitable probe designs and manufacturing materials compatible with Raman spectroscopy.

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“…The advantage will be in the ability to inscribe the gratings in all the single-mode cores (the multicore fiber) simultaneously, rather than in each single-mode fiber separately. However, the major technological challenge in this concept is the realization of high quality fiber Bragg gratings in multicore fibers with such large numbers of cores, but recent published results on the fabrication of fiber Bragg gratings in multicore fibers [13,35] have been promising.…”

Section: Astronomy and Spectroscopymentioning

confidence: 99%

Photonic lanterns

2013

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Multimode optical fibers have been primarily (and almost solely) used as "light pipes" in short distance telecommunications and in remote and astronomical spectroscopy. The modal properties of the multimode waveguides are rarely exploited and mostly discussed in the context of guiding light. Until recently, most photonic applications in the applied sciences have arisen from developments in telecommunications. However, the photonic lantern is one of several devices that arose to solve problems in astrophotonics and space photonics. Interestingly, these devices are now being explored for use in telecommunications and are likely to find commercial use in the next few years, particularly in the development of compact spectrographs. Photonic lanterns allow for a low-loss transformation of a multimode waveguide into a discrete number of single-mode waveguides and vice versa, thus enabling the use of single-mode photonic technologies in multimode systems. In this review, we will discuss the theory and function of the photonic lantern, along with several different variants of the technology. We will also discuss some of its applications in more detail. Furthermore, we foreshadow future applications of this technology to the field of nanophotonics.

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Multicore fiber with integrated fiber Bragg gratings for background-free Raman sensing

Cited by 54 publications

References 31 publications

Raman spectroscopy: techniques and applications in the life sciences

Raman spectroscopy: techniques and applications in the life sciences

Developing fibre optic Raman probes for applications in clinical spectroscopy

Photonic lanterns

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