Multicolor Scanning Laser Imaging in Lipemia Retinalis

Parra, David Rivera-De la; Pérez-Peralta, Liliana; Toldi, Jim; Levine, Jason; Fikhman, Michael; Graue-Hernández, Enrique O

doi:10.1097/icb.0000000000000469

Cited by 11 publications

(1 citation statement)

References 9 publications

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“…There have been previous reports regarding color fundus photography, spectral-domain optical coherence tomography (SD-OCT), multicolor laser scanning, and electrophysiologic findings in lipemia retinalis [ 14 – 17 ]. However, to the best of our knowledge, analysis of the microcirculation and retinal oxygenation in lipemia retinalis has not been reported previously.…”

Section: Introductionmentioning

confidence: 99%

Alterations in ocular microcirculation and oxygen metabolism in patients with lipemia retinalis

Alsarhani

Adel²,

Alamri³

et al. 2022

BMC Ophthalmol

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Purpose The study aims to assess the alterations in retinal oxygen saturation and retinal and choroidal blood flow in lipemia retinalis. Methods This was a cross-sectional study on 10 eyes (5 patients) with history of lipemia retinalis. The study comprised 10 eyes with documented history of lipemia retinalis and 10 participants as healthy controls. Patients with a confirmed history of lipemia retinalis were grouped into two cohorts based on their most recent fundus examination: untreated lipemia retinalis (abnormal fundus) and resolved lipemia retinalis (normal fundus). Both retinal arteriolar and venular oxygen saturation were measured using the non-invasive spectrophotometric retinal oximeter (Oxymap T1). The mean blur rate (MBR) of the optic nerve and choroidal blood flow were analyzed using a laser speckle flowgraph (LSFG). Results Patients with untreated lipemia retinalis had a significantly higher retinal arteriolar and venular oxygen saturation than that of the other two groups (p < 0.001). Moreover, patients with untreated lipemia retinalis had significantly smaller retinal arteriolar and venular diameters (p < 0.001). On LSFG, there was a significant difference in the overall MBR (p = 0.007) and vessel MBR of the optic nerve between the groups (p = 0.011). The patients with history of lipemia retinalis (untreated and resolved) exhibited a high overall MBR and vessel MBR of the optic nerve than that of the control group. There was a significant elevation of the optic nerve (p = 0.002) and choroidal blowout score (p < 0.001), while the resistivity index of the optic nerve (p = 0.001) and choroids (p = 0.002) was significantly lower in patients with resolved and untreated lipemia retinalis. Conclusions There was a significant alteration in retinal oximetry, in untreated lipemia retinalis, and in retinal blood flow, in both the resolved and untreated groups. The increase in retinal blood flow and oxygen saturation may elucidate the preservation of visual acuity and function despite the fundus changes observed in lipemia retinalis.

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Section: Introductionmentioning

confidence: 99%

Alterations in ocular microcirculation and oxygen metabolism in patients with lipemia retinalis

Alsarhani

Adel²,

Alamri³

et al. 2022

BMC Ophthalmol

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Clinical application of multicolour scanning laser imaging in diabetic retinopathy

Wang

et al. 2018

Lasers Med Sci

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To compare the visualization of the lesions of diabetic retinopathy (DR) using multicolour scanning laser imaging (MSLI) and conventional colour fundus photography (CFP). The paired images of diabetic patients who underwent same-day MSLI and CFP examinations were reviewed. Combined multicolour (MC) images were acquired simultaneously using three laser wavelengths: blue reflectance (BR, λ = 488 nm), green reflectance (GR, λ = 518 nm) and infrared reflectance (IR, λ = 820 nm). The number of positive DR lesions was calculated using fundus fluorescein angiography as the reference standard. The visibility of the microaneurysms (Mas) was graded using a scale, and the number of Mas for each method was counted by two masked readers. Eighty eyes of 42 diabetic patients were included. The average grading score for Mas visualization was significantly higher with MC (1.50 ± 0.71) and GR (1.55 ± 0.69) than with CFP (0.95 ± 0.81). The average number of Mas was also significantly higher with MC (11.41 ± 14.02) and GR (11.93 ± 13.43) than with CFP (6.43 ± 9.39). The number of positive Mas, diabetic macular edema (DME) and epiretinal membranes (ERM) were significantly higher with MC than CFP (P < 0.05), while the numbers of cotton wool spots, haemorrhages, hard exudates, venous beading and abnormal new vessels were not significantly different (P > 0.05). Mas and ERM were most effectively detected on GR images, and an elevated greenish shift was clearly visualized in patients with DME on the MC images. MSLI can effectively visualize Mas and other pathological lesions of DR compared with CFP. MSLI with superior resolution may be a useful complement for DME and ERM detection.

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Lipemia retinalis as the presenting sign of undiagnosed type 1 diabetes mellitus resulting in severe secondary hypertriglyceridemia

Trese

Price

Bohra

2018

Journal of American Association for Pediatric Ophthalmology and

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Multicolor Scanning Laser Imaging in Lipemia Retinalis

Cited by 11 publications

References 9 publications

Alterations in ocular microcirculation and oxygen metabolism in patients with lipemia retinalis

Alterations in ocular microcirculation and oxygen metabolism in patients with lipemia retinalis

Clinical application of multicolour scanning laser imaging in diabetic retinopathy

Lipemia retinalis as the presenting sign of undiagnosed type 1 diabetes mellitus resulting in severe secondary hypertriglyceridemia

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