Multicentric giant cell tumor in adolescents

Jung, Sung-Taek; Park, Hyeong-Won; Lee, Dong-Hyun; Choi, Jun-Ik

doi:10.1097/bpb.0b013e32835470da

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…Multicentric GCT of bone has been described in adults but is exceedingly rare in children. Literature review revealed 10 cases of metachronous multicentric GCT of bone in children, [3][4][5][6][7] ranging in age from 10 to 16 years, male to female ratio of 3:7 and involving 2-10 sites over a span of 1-15 years (Table 1). In most reports, the second lesion was more aggressive than the first, recurrence was common, and curettage was ineffective as treatment with majority requiring wide resection and reconstruction.…”

Section: Discussionmentioning

confidence: 99%

Metachronous multicentric giant cell tumour of bone in a 12-year-old girl: A case report and review of literature

Wadia

Chaudhary

Anchan

et al. 2021

Journal of Orthopaedics, Trauma and Rehabilitation

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While giant cell tumour of bone is a relatively common tumour in adults, it is exceedingly rare in children. Multicentric metachronous giant cell tumour is an even rarer presentation of this tumour in skeletally immature patients. We present here the challenges in management of this rare tumour. A 12-year-old girl presented with a giant cell tumour affecting four different bones sequentially, three times within a 3-year period. The disease first appeared in the right distal fibula, then a year later in ipsilateral talus and calcaneus and finally a year later, in the T5 vertebral body, all requiring surgical treatment. Our strategy was to manage this lesion aggressively based on the limited literature available and present our own long-term surveillance strategy. Our patient responded well to treatment each time and has remained disease-free for 24 months from her last surgery. This is a rare case of metachronous multicentric giant cell tumour of bone in a skeletally immature patient requiring aggressive treatment and surveillance.

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Section: Discussionmentioning

confidence: 99%

Metachronous multicentric giant cell tumour of bone in a 12-year-old girl: A case report and review of literature

Wadia

Chaudhary

Anchan

et al. 2021

Journal of Orthopaedics, Trauma and Rehabilitation

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“…Multisentrik DHT çok nadirdir (<%1) ve en sık ekstremitenin distalinde el ve ayaklarda görülür. [2,4,7,8] DHT metafizer yerleşimli bir lezyon olmasına karşın trokantör majör gibi epifiz eşdeğeri olan apofizer böl-gelerde de nadiren karşımıza çıkmaktadır. Bu durumlarda etrafında skleroz olmayan litik lezyon görünümü-ne rastlanmayabilir.…”

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Kemiğin dev hücreli tümörü

Deveci¹

2013

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Giant cell tumor of bone at the proximal epiphysis of humerus in a skeletally immature patient: A case report

Ramírez-González

Olivella

Ramírez

et al. 2020

International Journal of Surgery Case Reports

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Highlights Giant cell tumor of bone (GCTB) at proximal humerus in skeletally immature (SI) patients is rare. MRI and clinical evaluation are paramount for the GCTB diagnosis. Tumor resection with cementation and adjuvant therapy is described as GCTB treatment. GCTB should be suspected in all SI cases with enlarged proximal humerus lesions.

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Multicentric giant cell tumor in adolescents

Abstract: The presentation of multicentric giant cell tumor in adolescents with an open physis is very rare. We report three cases of a multicentric giant cell tumor of the bone in adolescents, and a review of the literature is also presented.

Cited by 4 publications

References 22 publications

Metachronous multicentric giant cell tumour of bone in a 12-year-old girl: A case report and review of literature

Metachronous multicentric giant cell tumour of bone in a 12-year-old girl: A case report and review of literature

Kemiğin dev hücreli tümörü

Giant cell tumor of bone at the proximal epiphysis of humerus in a skeletally immature patient: A case report

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