2014
DOI: 10.1002/bjs.9684
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Multicentre analysis of long-term outcome after surgical resection for gastric cancer liver metastases

Abstract: Clinically resectable GCLM is rare, but strict and careful patient selection can lead to long-term survival following R0 surgical resection.

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Cited by 118 publications
(142 citation statements)
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“…The number of positive PALNs has also been pointed out as a prognostic factor in previous studies (4,20). As in patients with limited metastatic gastric cancer, the number of liver metastases (one or two) has been identified as a prognostic factor after surgical resection when no extrahepatic metastasis is present (21). It is presumed that the number of lesions might be a pivotal factor associated with the prognosis in such patients with limited metastasis.…”
Section: Discussionmentioning
confidence: 90%
“…The number of positive PALNs has also been pointed out as a prognostic factor in previous studies (4,20). As in patients with limited metastatic gastric cancer, the number of liver metastases (one or two) has been identified as a prognostic factor after surgical resection when no extrahepatic metastasis is present (21). It is presumed that the number of lesions might be a pivotal factor associated with the prognosis in such patients with limited metastasis.…”
Section: Discussionmentioning
confidence: 90%
“…Those results were maintained after propensity matching for the differences between groups. Other publications from the Far East [4][5][6][7], and some Western centers [14][15][16][17], have also suggested the safety of hepatectomy for gastric cancer liver metastases in selected patients. The results of this study also parallel the outcomes of hepatectomy for colorectal cancer liver metastases, where surgical resection is more common and is considered the standard of care for isolated hepatic metastases [11].…”
Section: Discussionmentioning
confidence: 99%
“…Gastrectomy in Eastern centers is associated with improved long-term survival compared to the West after controlling for disease stage and patient demographics [3]. Furthermore, in Eastern centers more attention has been given to the surgical treatment of liver metastases from gastric cancer [4][5][6][7] and toward gastrectomy as a reduction surgical strategy in the presence of a single noncurable factor that showed no survival improvement over chemotherapy alone [8].…”
Section: Introductionmentioning
confidence: 99%
“…Even though almost all studies were small retrospective series, a limited number and small size of LM were favorable prognostic factors in patients who undergo hepatectomy. One multicenter retrospective analysis of 256 patients reported a promising median OS of 31.1 months [14]. A propensity-matched analysis using a national database in the United Kingdom showed that the prognosis of patients who underwent both gastrectomy and hepatectomy was better than of those who received no surgery [15].…”
Section: Introductionmentioning
confidence: 99%