Multicenter Study of Hospital-Acquired Pneumonia in Non-ICU Patients

Understanding factors that impact on public and patient’s risk perceptions and responses toward Clostridium difficile and other health care-associated infections: A structured literature review

“…This is similar to rates reported in other studies: in the HAPPI-1 study, 3 the rate of unreported NV-HAP was 1.25 cases per 1,000 patient days before intervention, and in 1 study on non-ICU HAP, 3 ± 1.4 cases per 1,000 hospital admissions were reported. 30 Although previous studies indicate that most NV-HAP cases occur in older patients, 31 we found that over half of NV-HAP cases (50.9%) were in patients <66 years of age. Although increased age is a known independent risk factor for NV-HAP, 31 our findings support that younger patients are also at some risk and do acquire pneumonia while hospitalized.…”

Detection of Legionella pneumophila serogroup 1 in blood cultures from a patient treated with tumor necrosis factor-alpha inhibitor

“…The reported incidence of LD in CAP ranges from 1.6% to 7.5% [2][3][4][5][6] and that in severe CAP is between 14% and 22.8%) [6][7][8]. Legionnaires' disease has appeared in hospitals, long-term care facilities and other types of accommodation [9][10][11][12][13][14][15], causing serious problems. Rapid diagnosis is important to prevent LD outbreaks.…”

Four country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections

“…Much of the data on pneumonia published elsewhere focusses on the ventilated patient in the intensive care unit, where S. aureus is a common and important cause, [8][9][10][11] but there is relatively little data on patients outside critical care units. In our study, MRSA was more common in LRTIOP, not commonly described in ventilated patients compared with pneumonia, and as LRTIOP includes empyema, it is often a more prolonged illness and this impacts on prevalence.…”

“…12 Deleted: In a prospective study in Spain, the incidence of hospital-acquired pneumonia was three cases/1,000 hospital admissions and an aetiological agent was obtained in 36.4% of cases. 8 When comparing the outcomes from two different treatments in 544 patients with VAP, S. aureus was the most commonly identified pathogen, recovered in 221 patients, including 91 with MRSA. 9 In a retrospective analysis of pooled patient data from multiple clinical trials in France, patients with MRSA VAP were significantly older than those with meticillin-susceptible S. aureuswho had a median duration of mechanical ventilation of eight days, compared with 13 days for patients with MRSA.…”

“…9 In a retrospective analysis of pooled patient data from multiple clinical trials in France, patients with MRSA VAP were significantly older than those with meticillin-susceptible S. aureuswho had a median duration of mechanical ventilation of eight days, compared with 13 days for patients with MRSA. 10 In a study by Shorr and colleagues, patients with MRSA had a longer stay in the ICU and their treatment was associated with considerable higher costs (US $7,731) per Deleted: Although antibiotic-associated diarrhoea due to C. difficile was first ... [6] ... [4] ... [5] ... [2] ... [3] ... [1] ... [7] ... [8] HIS06-RTI(9) 240609 Page 10 of 16 A higher proportion of infections were recorded as being due to MRSA in patients with LRTIOP (18.1%) compared with pneumonia (7.6%), and C. difficile was also more common in the LRTIOP group. This may suggest poor specificity in the diagnosis of LRTIOP, i.e.…”