Multicenter Study of Endocarditis After Transcatheter Pulmonary Valve Replacement

Not Your Usual Case of Culture-Negative Endocarditis: A Case Report of Bartonella Endocarditis

“…However, an important long-term complication is valvular dysfunction secondary to IE with the risk extending over several years following valve implantation with reported rates higher than those related to pulmonary homograft [ 4 ]. There is limited data exploring risk factors and outcomes of IE in TPVI, but a recent multicenter study has revealed that younger age, a prior episode of IE, and a higher residual gradient were associated with endocarditis [ 5 ]. The pathophysiologic mechanism driving endocarditis in this subgroup remains unclear; however, many theorize that thrombus formation in patients with poor compliance to aspirin therapy is an impactful first step [ 6 ].…”

Outcomes of Transcatheter Pulmonary Valve Replacement and Surgical Pulmonary Valve Replacement: A Cohort Analysis

“…The development of Melody valve implantation in the early 2000s 36 was originally intended to extend the longevity of the RVOT conduit. Although these procedures were performed in >12,000 patients worldwide, 10,21,37 they were not readily applicable in most patients with TOF with native RVOT and severe PR. The Edwards SAPIEN S3 valve 13,38,39 could be invertedly mounted on the Commander system for PV implantation.…”

“…Large, balloon-expandable stent placement in the right side of the heart, such as in the conduit or branch pulmonary artery, is a familiar procedure performed in our biplane congenital heart intervention cardiac catheterization suites for decades. This relevant experience can shorten the learning curve for the operator and team, with success rates as high as 80% 13,[37][38][39][40] for patients with RVOT conduit and obtained a class I indication for TPVR by the European Society of Cardiology. 9 For patients with native RVOT, the success rate could also be improved by an additional type of TPVR system, such as a self-expandible system Venus P-valve 14 or Pulsta valve 15 to accommodate different types of RVOT anatomy.…”

A Rare Case of Infective Mediastinitis after Melody Valve Implantation

“…In a recent study reporting a post-Melody PVE rate of 2.4% patient-year, Bos et al [10] underscored that 20% of those patients presented either with severe sepsis and/or heart failure, and 30% with severe RVOT obstruction [10]. Similarly in his recent large-scale multi-centric study, McElhinney et al [11] reported an annualized incidents of 2.2% patient-year. Endocarditis was severe in 44% of the patients, resulting in an overall mortality rate of 6.6%.…”