Multicenter retrospective study on management and outcome of newborns affected by surgical necrotizing enterocolitis

Federici, Silvana; Biagi, Lorenzo De; Straziuso, Simona; Leva, Ernesto; Brisighelli, Giulia; Mattioli, Girolamo; Pio, Luca; Bagolan, Pietro; Totonelli, Giorgia; Noccioli, Bruno; Severi, Elisa; Chiesa, Pierluigi Lelli; Lisi, Gabriele; Tramontano, Antonino; Chiara, Carolina De; Rossi, Carmine Del; Casadio, Giovanni; Messina, Mario; Angotti, Rossella; Appignani, Antonino; Bertozzi, Mirko; Rossi, Fábio; Gabriele, Valeria; A, Franchella; Zocca, Veronica

doi:10.23736/s0026-4733.17.07159-0

Cited by 8 publications

(1 citation statement)

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“…Digestive surgery in neonates could lead to a challenging and life-threatening situation ( 5 ). In “Case report: Spindle cell neoplasm presenting as a spontaneous intestinal perforation in a term infant”, Callaghan describes a rare case of neonatal intestinal perforation related to a spindle cell tumor, focusing on genetic assessment and the molecular signature of this particular neoplasm.…”

Section: Oncology Diseasesmentioning

confidence: 99%

Editorial: Case reports in pediatric surgery 2022

2023

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Section: Oncology Diseasesmentioning

confidence: 99%

Editorial: Case reports in pediatric surgery 2022

2023

Self Cite

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Clinical characteristic comparison of low birth weight and very low birth weight preterm infants with neonatal necrotizing enterocolitis: a single tertiary center experience from eastern China

et al. 2018

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Laser Speckle Contrast Imaging to Evaluate Bowel Lesions in Neonates with NEC

Knudsen

Thorup

Strandby

et al. 2017

European J Pediatr Surg Rep

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Background Necrotizing enterocolitis (NEC) is the most frequent surgical emergency in newborns. Intestinal ischemia is considered a factor that precedes the development of NEC lesions. Laser speckle contrast imaging (LSCI) can be used to assess tissue microcirculation. We evaluated if LSCI may help to detect intestinal regions with reduced microcirculation in NEC. Case Report A male patient (gestational age, 26 [3/7] weeks; birth weight, 600 g) showed clinical signs of NEC 28 days after birth. X-ray revealed pneumatosis intestinalis and portal gas. Laparotomy showed NEC lesions with signs of transmural ischemia in the terminal ileum and cecum. Surgical resection lines (RLs) were marked, followed by LSCI measurements and resection of the bowel between the two RLs. Post hoc LSCI analyses were conducted on both sides of the proximal and distal RL. Low-flux values, indicating reduced microcirculation, were found in the macroscopically assessed necrotic bowel at the proximal RL, whereas higher flux values, indicating sufficient microcirculation, were found in the macroscopically assessed normal bowel. Discussion This study is the first description of intra-abdominal use of LSCI to evaluate tissue microcirculation in relation to NEC lesions. LSCI could be a valuable tool to distinguish between ischemic and nonischemic bowel in neonates undergoing surgery for NEC.

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Multicenter retrospective study on management and outcome of newborns affected by surgical necrotizing enterocolitis

Cited by 8 publications

References 0 publications

Editorial: Case reports in pediatric surgery 2022

Editorial: Case reports in pediatric surgery 2022

Clinical characteristic comparison of low birth weight and very low birth weight preterm infants with neonatal necrotizing enterocolitis: a single tertiary center experience from eastern China

Laser Speckle Contrast Imaging to Evaluate Bowel Lesions in Neonates with NEC

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