Multicenter Experience with Upper Gastrointestinal Polyps in Pediatric Patients with Familial Adenomatous Polyposis

Abstract

All pediatric patients with FAP warrant upper gastrointestinal screening and surveillance endoscopy from the time of initial colonoscopy irrespective of referable symptoms. Patients with APC mutation between codon 1225-1694 may be more susceptible to aggressive gastroduodenal involvement in FAP.

An ileal hyperplastic polyp comorbidity in the case of acute appendicitis

“…Hereditary hamartomatous polyps and mainly hereditary adenomatous polyposis have malign transformation potential and may be seen together with extraintestinal benign and malign neoplasms. [4][5][6] Although intestinal polypoidal nodular hyperplasia can be seen in all age groups, they are more common in pediatric age groups. [6] Rectal and ileocecal intestinal segments are the most common sites.…”

“…[4][5][6] Although intestinal polypoidal nodular hyperplasia can be seen in all age groups, they are more common in pediatric age groups. [6] Rectal and ileocecal intestinal segments are the most common sites. Intestinal polypoidal hyperplasias are characterized as benign lesions and viral or parasitic infections are their main etiological factors.…”

“…Commonly, they don't occur in stalk formation (as sessile) and mostly they are in solid appearance. [6,7] Sometimes more than one intestinal polypoidal hyperplasias can be observed at different point of intestinal segment.…”

“…Sometimes spontaneous remission of these polyps may occur. [6,7] The rectosigmoidal segment of intestin is the most common site for polyps to occur, followed by the other side of intestinal segments. Multiple segmental diseases may also be observed.…”

“…Patients with the following features should be evaluated endoscopically for polypoidal diseases: Patients with positive family history, symptomatic patients during follow up and patients with extraintestinal polyp related diseases. [6][7][8][9] Wireless capsule endoscopy is a technology developed recently for the endoscopic exploration of the small bowel which otherwise can not be visualized by conventional techniques. It is first and essential indication was occult gastrointestinal bleeding and intestinal polyp like diseases.…”