Multicenter Clinicopathological Study of High-Grade Serous Carcinoma Presenting as Primary Peritoneal Carcinoma

Abstract

This study identified various characteristics of clinical PPC. Neoadjuvant chemotherapy with IDS is a reasonable treatment strategy, and complete debulking surgery is optimum.

Rare primary peritoneal mucinous adenocarcinoma in a 69‐year‐old man

“…The phenomenon has been called as müllerian epithelial metaplasia or the secondary müllerian system 23,24 . However, a novel important finding has recently been described: Primary peritoneal adenocarcinomas of women originate from carcinoma in situ of the fallopian tube at the distal end (fimbriae) of the tube of müllerian origin 4,5 …”

“…2 , 3 Recently, a new theory has been proposed for the origin of peritoneal carcinoma in women; namely, the primary site is supposed to be located at the distal fimbrial end of the fallopian tube. 4 , 5 …”

“…Serous adenocarcinoma accounts for the majority of primary peritoneal carcinoma, with histopathological features identical to those of ovarian origin, while mucinous adenocarcinoma, endometrioid adenocarcinoma, and clear cell carcinoma are rare 2,3 . Recently, a new theory has been proposed for the origin of peritoneal carcinoma in women; namely, the primary site is supposed to be located at the distal fimbrial end of the fallopian tube 4,5 …”

“…2,3 Recently, a new theory has been proposed for the origin of peritoneal carcinoma in women; namely, the primary site is supposed to be located at the distal fimbrial end of the fallopian tube. 4,5 So far, only a small number of male cases of primary serous adenocarcinoma of the peritoneum have been reported, [6][7][8][9][10][11] In 2018, Wang, et al described a male case of primary peritoneal mucinous adenocarcinoma, as the rarest of the rare. 12 This should be the second case of primary peritoneal mucinous adenocarcinoma in a man.…”

Clinically diagnosed primary transitional cell carcinoma of the colon: A case report

“…In ovarian cancer, TCC represents a poorly differentiated form of high-grade serous carcinoma [12]. Primary peritoneal carcinoma presents high-grade serous carcinoma [13]. It might be a possibility, therefore, that primary peritoneal carcinoma invaded the colon and presented TCC in the colon.…”