Multi-walled Carbon Nanotubes/Graphite Nanosheets Modified Glassy Carbon Electrode for the Simultaneous Determination of Acetaminophen and Dopamine

Abstract

Graphite nanosheets prepared by thermal expansion and successive sonication were utilized for the construction of a multi-walled carbon nanotubes/graphite nanosheets based amperometric sensing platform to simultaneously determine acetaminophen and dopamine in the presence of ascorbic acid in physiological conditions. The synergistic effect of multiwalled carbon nanotubes and graphite nanosheets catalyzed the electrooxidation of acetaminophen and dopamine, leading to a remarkable potential difference up to 200 mV. The as-prepared modified electrode exhibited linear responses to acetaminophen and dopamine in the concentration ranges of 2.0 × 10 -6 -2.4 × 10 -4 M (R = 0.999) and 2.0 × 10 -6 -2.0 × 10 -4 M (R = 0.998), respectively. The detection limits were down to 2.3 × 10 -7 M for acetaminophen and 3.5 × 10 -7 M for dopamine (S/N = 3). Based on the simple preparation and prominent electrochemical properties, the obtained multiwalled carbon nanotubes/graphite nanosheets modified electrode would be a good candidate for the determination of acetaminophen and dopamine without the interference of ascorbic acid.

Porous carbon nanosheets derived from two-dimensional Fe-MOF for simultaneous voltammetric sensing of dopamine and uric acid

“…DA and UA can be detected by working electrodes modified by various multi-dimensional nanocomopsites, such as such as zero-dimensional quantum dots, one-dimensional nanotubes, two-dimensional (2D) nanoplates, and threedimensional (3D) porous aerogel [19][20][21][22][23]. Among them, 2D nanocomposites are one of the preferred choice materials for preparing various electrochemical sensors, especially for wear devices, because of their unique electrical, mechanical, chemical, and structural properties [24,25].…”

The New Application of Boron Doped Diamond Electrode Modified with Nafion and Lead Films for Simultaneous Voltammetric Determination of Dopamine and Paracetamol

“…Many papers describe the application of modified electrodes to DA and PA assay. It is common to use a multiwalled carbon nanotubes modified glassy carbon electrode which are additionally acid functionalized or modified with graphene oxide , disordered mesoporous silica , cobalt nanoparticles , nickel(II) hydroxide nanoparticles and MCM‐41molecular sieve or graphite nanosheets . Other working electrodes used for the simultaneous voltammetric determination of DA and PA are: single‐wall carbon nanotubes modified carbon‐ceramic electrode , pyrolytic carbon film electrode , poly overoxidized pyrrole‐aszophloxine‐gold modified electrode , glassy carbon electrode modified with (4‐ferrocenylethyne) phenylamine functionalized graphene sheets coupling with chitosan , glassy carbon electrode modified with nanocomposite of ferrocene thiolate stabilized Fe 3 O 4 @Au nanoparticles with graphene sheet/chitosan , glassy carbon electrode modified with highly loaded zirconium oxide nanoparticles decorated reduced graphene oxide , glassy carbon electrode modified with Ag‐nanoparticle with 4‐nitro phenylcyanamide ligand , glassy carbon electrode modified with porous gold nanosheets or PbS nanoparticles Schiff base‐modified carbon paste electrode .…”