Multi-walled carbon nanotube dispersion by the adsorbed humic acids with different chemical structures

Zhang, Di; Pan, Bo; Cook, Robert L.; Xing, Baoshan

doi:10.1016/j.envpol.2014.10.020

Cited by 40 publications

(24 citation statements)

References 39 publications

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“…In addition, the activation of PPAR-g promotes adipogenesis and the suppression of PPAR-g pathway may inhibit adipogenesis and stimulate osteoblast differentiation (Zhang et al, 2015). In the present study, the treatment of 0.06-6 mg/mL HETF decreased the expression level of PPAR-g to 0.82-, 1.0-, and 0.79-folds, which was consistent with oil red O staining and quantification.…”

Section: Discussionsupporting

confidence: 74%

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway

Zhang

Liu

Jia

et al. 2015

Pharmaceutical Biology

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Objective: The present study investigates the effect of total flavonoids of Herba Epimedii (HETF) on the osteogenesis and adipogenesis of primary MSCs. Materials and methods: HETF were prepared and identified by HPLC-fingerprinting, primary mouse MSCs in the presence of 0.006-6 mg/mL HETF for 2-10 d were subject to morphological, biochemical, and quantitative real-time PCR analysis. Results: Sixteen chemical components were identified in HETF by HPLC-fingerprinting and account for over 95% of the total area of HPLC peaks. During osteogenesis of MSCs, 0.006-6 mg/mL HETF promoted the proliferation of MSCs from 17% to 22%, increased alkaline phosphatase activity up to 3.7-fold (0.6 mg/mL), and extracellular calcium deposits from 1.2-to 1.4-folds by up-regulating the expression of runt-related transcription factor-2 (Runx-2) and bone morphogenetic protein-2 (BMP-2). Meanwhile, HETF suppressed the adipogenesis of MSCs by reducing the formation of adipocytelike cells and accumulation of fat droplets by down-regulating the expression of peroxisome proliferator-activated receptor-g (PPAR-g). The above biological activities of HETF were mainly through estrogen receptor-mediated pathway, which were blocked by estrogen receptor antagonist, ICI 182,780. Conclusion: HETF could regulate Runx-2-mediated osteogenesis and PPAR-g-mediated adipogenesis in MSCs and thus exhibit beneficial effects to bone health, which suggests a new strategy for treating patients with osteoporosis and obesity.ARTICLE HISTORY

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Section: Discussionsupporting

confidence: 74%

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway

Zhang

Liu

Jia

et al. 2015

Pharmaceutical Biology

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“…119-121 ENMs can conditionally sorb and modulate the toxicity and uptake of other contaminants and vice versa. 122-134 ENMs can acquire coatings 135, 136 such as natural organic matter (NOM), 137, 138 and age with varying pH and sunlight. 139, 140 Assessment outcomes are affected by media chemistry, physical characteristics, and additives (e.g., soil pH, 141 temperature, 142 or organic matter content, 108, 143 and dispersing agents in aqueous media 144 ).…”

Section: What Exposure Conditions Are Used In Assessing Enm Ecologicamentioning

confidence: 99%

Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials

Holden

Gardea‐Torresdey

Klaessig

et al. 2016

Environ. Sci. Technol.

Self Cite

197

150

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Engineered nanomaterials (ENMs) are increasingly entering the environment with uncertain consequences including potential ecological effects. Various research communities view differently whether ecotoxicological testing of ENMs should be conducted using environmentally relevant concentrations—where observing outcomes is difficult—versus higher ENM doses, where responses are observable. What exposure conditions are typically used in assessing ENM hazards to populations? What conditions are used to test ecosystem-scale hazards? What is known regarding actual ENMs in the environment, via measurements or modeling simulations? How should exposure conditions, ENM transformation, dose, and body burden be used in interpreting biological and computational findings for assessing risks? These questions were addressed in the context of this critical review. As a result, three main recommendations emerged. First, researchers should improve ecotoxicology of ENMs by choosing test endpoints, duration, and study conditions—including ENM test concentrations—that align with realistic exposure scenarios. Second, testing should proceed via tiers with iterative feedback that informs experiments at other levels of biological organization. Finally, environmental realism in ENM hazard assessments should involve greater coordination among ENM quantitative analysts, exposure modelers, and ecotoxicologists, across government, industry, and academia.

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“…The linear, Freundlich, and Langmuir models were applied to describe the adsorption isotherms (Lerman et al, 2013;Zhang et al, 2015):…”

Section: Discussionmentioning

confidence: 99%

“…Aquatic colloids contain natural organic matters (NOMs), and NOMs can provide abundant adsorption sites for organic pollutants. Characteristics of NOMs played important roles for organic pollutants adsorption by CNTs (Sun and Zhou, 2014;Zhang et al, 2015). However, the adsorption of organic pollutants by I-NPs is much less than by NOMs.…”

Section: Adsorption Isothermsmentioning

confidence: 98%

Effect of inorganic nanoparticles on 17β-estradiol and 17α-ethynylestradiol adsorption by multi-walled carbon nanotubes

Sun

Zhang

et al. 2015

Environmental Pollution

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Multi-walled carbon nanotube dispersion by the adsorbed humic acids with different chemical structures

Cited by 40 publications

References 39 publications

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway

Flavonoids of Herba Epimedii stimulate osteogenic differentiation and suppress adipogenic differentiation of primary mesenchymal stem cells via estrogen receptor pathway

Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials

Effect of inorganic nanoparticles on 17β-estradiol and 17α-ethynylestradiol adsorption by multi-walled carbon nanotubes

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