Multi-target Compounds against Trypanosomatid Parasites and
Mycobacterium tuberculosis
Midiane Correia Gomes,
Emanuelly Karla Araújo Padilha,
Gustavo Rafael Angelo Diniz
et al.
Abstract:Multi-target drug treatment has become popular as a substitute for traditional monotherapy.
Monotherapy can lead to resistance and side effects. Multi-target drug discovery is gaining
importance as data on bioactivity becomes more abundant. The design of multi-target drugs is expected
to be an important development in the pharmaceutical industry in the near future. This review
presents multi-target compounds against trypanosomatid parasites (Trypanosoma cruzi, T.
brucei, and Leishmania sp.) and tuberculosis (M… Show more
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