Multi‐resistant Salmonella Typhimurium DT104 ‐ implications for animal industries and the veterinary profession

Salmonellaand on‐farm risk factors in healthy slaughter‐age cattle and sheep in eastern Australia

“…The identification of Salmonella spp and the on‐farm risk factors associated with their presence are necessary to devise effective controls to limit the spread of Salmonella directly to humans or indirectly through contaminated food 12–15 . Of the production systems studied, at the herd or flock level, the highest prevalence of non Dublin Salmonella spp was found in dairies (17%), followed by feedlots (13%).…”

“…The identification of Salmonella spp and the on-farm risk factors associated with their presence are necessary to devise effective controls to limit the spread of Salmonella directly to humans or indirectly through contaminated food. [12][13][14][15] Of the production systems studied, at the herd or flock level, the highest prevalence of non Dublin Salmonella spp was found in dairies (17%), followed by feedlots (13%). Based on the analysis of five pooled samples per property (each containing samples from five animals), dairy cattle were significantly more likely to shed Salmonella in faeces than the other pasture-based production animals: pasture beef cattle, mutton sheep and prime lambs (P < 0.05).…”

Salmonella Typhimurium persistence in a Hunter Valley dairy herd

“…Cattle are considered a major reservoir for human infections with Salmonella Typhimurium, 1 either by direct transmission or through manure contaminating meat and crops. S Typhimurium is by far the most common Salmonella serovar involved in human disease in Australia, 2 although Australia remains free of the bovine‐derived multiple drug resistant S Typhimurium DT104, which is of great concern in other countries 3 . The Australian cattle industry needs to be vigilant in monitoring salmonellosis and in understanding factors that affect its spread.…”

Mortality in Captive Elk from Salmonellosis

“…Salmonella typhimurium phage type 104 (DT104) was initially reported to cause higher hospitalization and mortality among humans than for other forms of salmonellosis (Wall et al, 1994), although more recent evidence failed to support this (Threlfall et al, 1998). This strain has become epidemic throughout North America and Europe (Crerar et al, 1999), and is resistant to at least five antimicrobials, including ampicillin, chloramphenicol, streptomycin, sulfonamides and tetracycline (R-type ACSSuT) (Besser et al, 1997). Based on molecular studies, the resistance genes are chromosomally encoded .…”