Multi-pesticide Residues Determination in Samples of Fruits and Vegetables Using Chemometrics Approach to QuEChERS-dSPE Coupled with Ionic Liquid-Based DLLME and LC–MS/MS

Lawal, A. O.; Wong, Richard C. S.; Tan, Guan Huat; Abdulra’uf, Lukman Bola; Alsharif, Ali Mohamed Ali

doi:10.1007/s10337-018-3511-7

Cited by 29 publications

(11 citation statements)

References 28 publications

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“…Notably, the best setup of mobile phases were also selected using the initial settings of the instrument. Therefore, the TCPA obtained from LC-MS/MS analysis serves as an index used for estimating the number of target analytes that are present in the analyzed samples (31). It is because of the close similarities range of the resulted peak areas due to the logP of targeted analytes.…”

Section: Conditioning Of the Lc-ms/msmentioning

confidence: 99%

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Lawal

Wong

2021

Journal of the Turkish Chemical Society Section A: Chemistry

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The selection of the best mobile phase setup is one of the most important factors to be considered prior to quantitative instrumentation of multiple pesticides. Usually, mobile phases comprises of water (A) and an organic solvent (B) are the setup used in liquid chromatography instruments for the analysis of pesticide residues in various samples. Unfortunately, most of the analyses are being carried out without optimization and selection of the best mobile phase setup to improve the sensitivity of the instrument. For that reason, the comparative analysis of the reportedly used mobile phases and some few suggested ones was carried out on the multi-pesticide mixture of 0.1 mg/kg (100 µg/kg) standard solutions and quantified with liquid chromatography-tandem mass spectrometry (LC-MS/MS) instrument. Consequently, the best mobile phases setup that resulted in the sum of average total chromatographic peak areas (ATCPAs) and average total chromatographic peak heights (ATCPH) for the total ion chromatography (TIC) scans as an index that correspond to the concentration levels was selected [0.1% formic acid in H 2O (A) and 0.1% formic acid in acetonitrile (ACN) (B)]. And further optimization was successfully carried out on the selected mobile phase-A and the resulted setup [1% ACN and 0.1% formic acid in Milli-Q-water (mobile phase A) coupled with 0.1% formic acid in ACN (mobile phase-B)] improved the instrumental sensitivity on the targeted analytes. Thus, this justify the potential benefits of optimizing setup of the mobile phases prior to LC-MS/MS instrumentation of multi-pesticide analytes.

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Section: Conditioning Of the Lc-ms/msmentioning

confidence: 99%

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Lawal

Wong

2021

Journal of the Turkish Chemical Society Section A: Chemistry

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“…Several approaches including solid-phase extraction (SPE), gel permeation chromatography (GPC), solid-phase microextraction (SPME), QuEChERS, dispersive-solid phase extraction (d-SPE) and matrix solid-phase dispersion (MSPD) have been attempted to eliminate lipids and coextracted interference from fatty food extracts. Among them, QuEChERS is the most used method for the analysis of muti-pesticides in the fruit and vegetable samples [24]. However, it is not applicable to fish sample due to the coextractive interference of lipids, fats, fatty acids and proteins in the matrix.…”

Section: Original Research Papermentioning

confidence: 99%

Multi-pharmaceuticals analysis in fish by continuous series solid-phase extraction coupled with UPLC-MS/MS

Gao

Wang

Chen

et al. 2021

AChrom

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Pharmaceuticals which are widely used in aquatic can easily migrate into the environment and aquatic animals, and can increase the risk of drug resistance and allergic symptoms if consumed by humans. In order to achieve high-throughput analysis of pharmaceuticals with different physical and chemical properties from complex matrices, we developed a new method for various types pharmaceuticals in fish and shrimp tissue. Series solid-phase extraction (s-SPE) with different adsorbents was selected for extracting and purifying analytes with different paddings. s-SPE were combined with ultra performance liquid chromatography triple quadruple tandem mass spectrometry (UPLC-MS/MS) for the detection of 30 pharmaceuticals antibiotics in fish samples. This method was stabilized and reliable to determinate the pharmaceuticals in fish and shrimp samples. As the method combined multiple Chinese national standards method, it could be easily treat the multi-pharmaceuticals from the fish and shrimp samples once time. It provided for both quantitative and qualitative methods and they could be applied to single- or multi-residue methods.

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“…The sample pre-treatment techniques include liquid-liquid extraction, liquid-solid extraction, shaking extraction, soxhlet extraction, supercritical uid extraction, pressurized solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, gel permeation chromatography, solid phase extraction, solid phase microextraction, molecularly imprinted polymers, matrix solid-phase dispersion, QuEChERS, cloud-point extraction, liquid phase microextraction, etc [18][19][20][21][22] . Automated solid-phase extraction system achieves arti cial intelligence in the sample pre-treatment techniques.…”

Section: Introductionmentioning

confidence: 99%

Study of Analytical Methods for Determining 16 Organophosphorus Pesticide Residues in Panax Notoginseng and Aucklandia Lappa Decne by Automated Solid-Phase Extraction System and GC/MS

Gou

Ruan

et al. 2021

Preprint

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A fast and sensitive multi-residue analytical method was developed for the determination of organophosphorus pesticide residues in Panax notoginseng and Aucklandia lappa decne by comparing an ultrasonic extraction and homogenate extraction approach coupled with automated solid-phase extraction system and gas chromatography-mass spectrometry (GC/MS). Various factors affecting the homogenate extraction and purification efficiency were investigated in detail. The optimum conditions for homogenate extraction of organophosphorus pesticide residues from Panax notoginseng and Aucklandia lappa decne were 60 mL dichloromethane, 10000 r/min of extracting revolution speed and 2 min of extracting time. The extracts were cleaned up by automated solid-phase extraction system and determined by GC/MS. Under the optimum conditions, the results of the homogenate extraction approach were compared with those of the ultrasonic extraction, and the homogenate extraction approach was used to extract the samples. The average recoveries of the method by a homogenate extraction approach coupled with automated solid-phase extraction system and GC/MS ranged from 72.56% to 96.70%, and RSDs were 0.05~0.14%, which allowed the determination of 16 organophosphorus pesticide residues in Panax notoginseng and Aucklandia lappa decne. The results indicated that the proposed method can apply for the determination of organophosphate pesticides residues in Panax notoginseng and Aucklandia lappa decne with high accuracy and precision.

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Multi-pesticide Residues Determination in Samples of Fruits and Vegetables Using Chemometrics Approach to QuEChERS-dSPE Coupled with Ionic Liquid-Based DLLME and LC–MS/MS

Cited by 29 publications

References 28 publications

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Multi-pharmaceuticals analysis in fish by continuous series solid-phase extraction coupled with UPLC-MS/MS

Study of Analytical Methods for Determining 16 Organophosphorus Pesticide Residues in Panax Notoginseng and Aucklandia Lappa Decne by Automated Solid-Phase Extraction System and GC/MS

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Multi-pesticide Residues Determination in Samples of Fruits and Vegetables Using Chemometrics Approach to QuEChERS-dSPE Coupled with Ionic Liquid-Based DLLME and LC–MS/MS

Cited by 29 publications

References 28 publications

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Optimization and Selection of Mobile Phase for the Determination of Multiple Pesticide Standards Using Liquid Chromatography-Tandem Mass Spectrometry

Multi-pharmaceuticals analysis in fish by continuous series solid-phase extraction coupled with UPLC-MS/MS

Study of Analytical Methods for Determining 16 Organophosphorus Pesticide Residues in Panax Notoginseng and Aucklandia&nbsp;Lappa Decne by Automated Solid-Phase Extraction System and GC/MS

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Study of Analytical Methods for Determining 16 Organophosphorus Pesticide Residues in Panax Notoginseng and Aucklandia Lappa Decne by Automated Solid-Phase Extraction System and GC/MS